dsDNA:Aim2 clusters bind Asc

Stable Identifier
R-MMU-877385
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
dsDNA:Aim2 clusters bind Asc
dsDNA:AIM2 clusters bind ASC via a PYD-PYD interaction.
Literature References
PubMed ID Title Journal Year
19158675 AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Hornung, V, Ablasser, A, Charrel-Dennis, M, Bauernfeind, FG, Horvath, G, Caffrey, DR, Latz, E, Fitzgerald, KA

Nature 2009
19158676 AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Fernandes-Alnemri, T, Yu, JW, Datta, P, Wu, J, Alnemri, ES

Nature 2009
Participants
Input
Output
Orthologous Events
dsDNA:AIM2 clusters bind ASC (Homo sapiens)
Authored
Jupe, S  (2010-06-14)
Reviewed
Kufer, TA  (2011-04-28)
Created
Jupe, S  (2010-06-14)
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