Reactome | Snapc3 [nucleoplasm]

Snapc3 [nucleoplasm]

Stable Identifier

R-MMU-83727

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

SNAPC3, Q9D2C9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
- RNA Polymerase III Transcription (Mus musculus)
  - RNA Polymerase III Transcription Initiation (Mus musculus)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Mus musculus)
      - Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Mus musculus)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc3 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9D2C9

Gene Names

Snapc3

Reference Genes

BioGPS Gene:77634 Snapc3

ENSEMBL:ENSMUSG00000028483

KEGG:mmu:77634 Snapc3

Monarch:77634 Snapc3

NCBI Gene:77634 Snapc3

UCSC:Q9D2C9 Snapc3

Reference Transcript

Other Identifiers

10505630

105193_at

1428760_at

1428761_a_at

1453077_a_at

1457731_at

163775_at

17415016

17415028

4365781

4474885

4475232

4503623

4693692

4722570

4770806

4810794

4816769

4921183

4923427

5036285

5051474

5055505

5095032

5136958

5242263

5308685

5319070

5360052

5412366

5494117

5541860

5553392

5565166

5603109

77634

97705_at

AA414991_rc_at

A_51_P463270

A_52_P217646

A_52_P35670

A_55_P1962926

GE1405137

GO:0000978

GO:0001006

GO:0001046

GO:0003677

GO:0003681

GO:0005634

GO:0005654

GO:0005730

GO:0006351

GO:0016073

GO:0016604

GO:0019185

GO:0042795

GO:0042796

ILMN_1213437

ILMN_1214738

ILMN_1227991

ILMN_2707634

ILMN_2903698

mMC024436

mMC025017

Participates

as a component of

SNAPc [nucleoplasm] (Mus musculus)

Inferred From

SNAPC3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_030109771.1, XP_011248436.1, XP_006538432.1, NP_084225.1, XP_006538433.1, XP_017175944.1

ENSEMBL

ENSMUSG00000028483, ENSMUSP00000124181, ENSMUSP00000124038, ENSMUST00000143533, ENSMUSP00000030206, ENSMUST00000124856, ENSMUST00000123262, ENSMUSP00000123793, ENSMUST00000030206

PRO

Q9D2C9

MGI

1916338

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