Reactome | Tmed10 [ER to Golgi transport vesicle membrane]

Tmed10 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-MMU-5689843

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

ER to Golgi transport vesicle membrane

Synonyms

TMED10, Q9D1D4

Locations in the PathwayBrowser

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Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Asparagine N-linked glycosylation (Mus musculus)
    - Transport to the Golgi and subsequent modification (Mus musculus)
      - ER to Golgi Anterograde Transport (Mus musculus)
        
        COPII-mediated vesicle transport (Mus musculus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Vesicle budding (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - ER to Golgi Anterograde Transport (Mus musculus)
    - COPII-mediated vesicle transport (Mus musculus)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - Vesicle budding (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Tmed10 [ER to Golgi transport vesicle membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9D1D4

Gene Names

Tmed10

Reference Genes

BioGPS Gene:68581 Tmed10

ENSEMBL:ENSMUSG00000021248

KEGG:mmu:68581 Tmed10

Monarch:68581 Tmed10

NCBI Gene:68581 Tmed10

UCSC:Q9D1D4 Tmed10

Reference Transcript

RefSeq:NM_026775.4 Tmed10

Other Identifiers

10401661

10408684

110384_at

1424707_at

1424708_at

1439444_x_at

1439462_x_at

1454688_x_at

17282723

4357928

4414345

4507532

4512705

4529239

4579525

4675564

4694118

4734345

4851038

4919757

4952510

5109496

5171212

5239319

5274419

5322713

5339651

5387186

5402846

5551190

68581

93336_at

A_51_P303238

A_51_P371993

A_55_P1983235

GE38274

GO:0000139

GO:0005215

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0005801

GO:0005886

GO:0006886

GO:0006888

GO:0006890

GO:0007030

GO:0008320

GO:0015031

GO:0016020

GO:0016192

GO:0019905

GO:0030134

GO:0030137

GO:0030140

GO:0030658

GO:0030667

GO:0031410

GO:0032732

GO:0033116

GO:0035964

GO:0042470

GO:0042589

GO:0043226

GO:0045055

GO:0048199

GO:0050714

GO:0055085

GO:0061024

GO:0070765

GO:0071806

GO:0106272

GO:0106273

GO:1902003

ILMN_2473337

ILMN_2643423

ILMN_2763255

ILMN_3002943

mMC008874

mMC021782

mMR026544

Participates

as a component of

TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Mus musculus)

Other forms of this molecule

Tmed10 [endoplasmic reticulum membrane]

Tmed10 [Golgi membrane]

Tmed10 [transport vesicle]

Tmed10 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

TMED10 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_081051.1

ENSEMBL

ENSMUST00000040766, ENSMUSP00000037583, ENSMUSG00000021248

PRO

Q9D1D4

GlyGen

Q9D1D4

MGI

1915831

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