p-S97-Bmal1:p-T451,T461-Clock binds Nampt gene

Stable Identifier
R-MMU-5663161
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
p-S97-Bmal1:p-T451,T461-Clock binds Nampt gene
The Bmal1:Clock (Arntl:Clock)heterodimer binds an E-box in the promoter of the Nampt gene and enhances transcription.
Literature References
PubMed ID Title Journal Year
19286518 Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

Nakahata, Y, Sahar, S, Astarita, G, Kaluzova, M, Sassone-Corsi, P

Science 2009
Participants
Input
Output
Orthologous Events
p-S90-BMAL1:p-T451,T461-CLOCK binds NAMPT gene (Homo sapiens)
Authored
May, B  (2015-01-15)
Reviewed
Albrecht, U  (2010-06-23)
Delaunay, F  (2010-06-23)
Hirota, T  (2010-06-23)
Kay, SA  (2010-06-23)
Albrecht, U  (2025-03-07)
Created
May, B  (2015-01-16)
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