Reactome | GNA12 [plasma membrane]

GNA12 [plasma membrane]

Stable Identifier

R-MMU-55355

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

P27600

Locations in the PathwayBrowser

Expand all

Hemostasis (Mus musculus)

- Platelet activation, signaling and aggregation (Mus musculus)
  - Thrombin signalling through proteinase activated receptors (PARs) (Mus musculus)
    - Thrombin-activated PARs activate G12/13 (Mus musculus)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Mus musculus)
        
        G-protein G12/G13 (active) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Mus musculus)
        
        G-protein alpha (12):GTP [plasma membrane] (Mus musculus)
        
        GNA12 [plasma membrane] (Mus musculus)
      - Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein G12/G13 (inactive) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Mus musculus)
        
        G-protein alpha (12):GDP [plasma membrane] (Mus musculus)
        
        GNA12 [plasma membrane] (Mus musculus)
    - Thrombin-activated PARs:G12/13 (active) dissociate (Mus musculus)
      - G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
        
        G-protein alpha (12):GTP [plasma membrane] (Mus musculus)
        
        GNA12 [plasma membrane] (Mus musculus)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Mus musculus)
        
        G-protein G12/G13 (active) [plasma membrane] (Mus musculus)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Mus musculus)
        
        G-protein alpha (12):GTP [plasma membrane] (Mus musculus)
        
        GNA12 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P27600

Reference Genes

BioGPS Gene:14673

ENSEMBL:ENSMUSG00000000149

ENSEMBL:ENSMUSG00000000149.11

KEGG Gene (Mus musculus):14673

Monarch:14673

NCBI Gene:14673

UCSC:P27600

Reference Transcript

RefSeq:NM_010302.2

Other Identifiers

10535273

1421026_at

1450097_s_at

1455008_at

14673

17454617

4367430

4623640

4705393

4763611

4911147

5412254

97226_at

97227_at

A_51_P385906

A_52_P647906

A_55_P2041788

GE35474

GO:0000166

GO:0001664

GO:0001701

GO:0003013

GO:0003824

GO:0003924

GO:0005525

GO:0005737

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007188

GO:0007266

GO:0008217

GO:0008360

GO:0009410

GO:0010762

GO:0016020

GO:0016328

GO:0016787

GO:0019001

GO:0019888

GO:0023052

GO:0030154

GO:0030163

GO:0031526

GO:0031683

GO:0031752

GO:0032006

GO:0032434

GO:0035556

GO:0042733

GO:0043005

GO:0043025

GO:0046872

GO:0048856

GO:0048870

GO:0051721

GO:0098772

GO:1904706

GO:1904753

ILMN_2686393

M63659_s_at

mMC021392

Participates

as a component of

Inferred From

GNA12 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034432.1

Ensembl

ENSMUST00000000153, ENSMUSG00000000149, ENSMUSP00000000153

PRO

P27600

MGI

95767

PDB

1ZCA

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