Reactome | (p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xp-T357,S358-MLKL [cytosol]

(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xp-T357,S358-MLKL [cytosol]

Stable Identifier

R-MMU-5218902

Type

Complex

Species

Mus musculus

Compartment

cytosol

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

p-S-RIPK1:p-S199,227-RIPK3 oligomer [cytosol] (Mus musculus)
x 4 phospho-p-T357,S358-MLKL [cytosol] (Mus musculus)

Participates

as an input of

MLKL binds ITCH (Mus musculus)
MLKL binds IP4, IP5 and IP6 (Mus musculus)

as a component of

p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Mus musculus)
p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol] (Mus musculus)

as an output of

RIPK3 phosphorylates MLKL (Mus musculus)

Inferred From

(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xp-T357,S358-MLKL [cytosol] (Homo sapiens)

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