Kat2b (Pcaf) acetylates Taf1b in SL1 Complex

Stable Identifier
R-MMU-5211235
Type
Reaction [transition]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Kat2b (Pcaf) acetylates Taf1b in SL1 Complex
Kat2b (Pcaf) and to a lesser extent Kat2a (Gcn5) acetylate the Taf1b (Taf(1)68) subunit of the SL1 complex. Acetylation of Taf1b is required for transcription of rRNA genes.
Literature References
PubMed ID Title Journal Year
11250901 Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription.

Muth, V, Nadaud, S, Grummt, I, Voit, R

EMBO J 2001
Participants
Input
Output
Catalyst Activity

acetyltransferase activity of Kat2b [nucleoplasm]

Physical Entity
Kat2b [nucleoplasm] (Mus musculus)
Activity
acetyltransferase activity (GO:0016407)
Orthologous Events
Acetylation of SL1 (Homo sapiens)
Authored
May, B  (2013-11-15)
Reviewed
May, B  (2014-01-21)
Created
May, B  (2013-12-09)
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