Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Il10rb [plasma membrane]
Stable Identifier
R-MMU-448423
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
IL10RB, Q61190
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-10 signaling (Mus musculus)
IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Mus musculus)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Mus musculus)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Mus musculus)
IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Mus musculus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
Interleukin-20 family signaling (Mus musculus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Mus musculus)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1, p-Y-STAT2, p-STAT3 [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Mus musculus)
IFNL2,IFNL3:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL10RB binds TYK2 (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Mus musculus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:p-Y705-STAT3 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:p-STAT1, p-STAT3 [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:p-STAT1, p-STAT3 [plasma membrane] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1, p-Y-STAT2, p-STAT3 [plasma membrane] (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:p-Y705-STAT3 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
Il10rb [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q61190
Gene Names
Il10rb
Reference Genes
ENSEMBL:ENSMUSG00000022969
UCSC:Q61190 Il10rb
Participates
as a component of
IL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
IL10RB:p-TYK2 [plasma membrane] (Mus musculus)
IL10RB:TYK2 [plasma membrane] (Mus musculus)
as an input of
IL10RB binds TYK2 (Mus musculus)
Inferred From
IL10RB [plasma membrane]
(Homo sapiens)
Cross References
PRO
Q61190
GlyGen
Q61190
MGI
109380
PDB
6WEO
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
