CHL1 interacts with NP-1

Stable Identifier
R-MMU-445078
Type
Reaction [binding]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CHL1 interacts with NP-1
CHL1 binds the Sema3A receptor, Neuropilin-1 (NP-1), via a conserved sequence in the Ig1 domain, and acts as obligate coreceptor to mediate Sema3A-induced growth cone collapse and axon repulsion.
Literature References
PubMed ID Title Journal Year
18077678 Close homolog of L1 and neuropilin 1 mediate guidance of thalamocortical axons at the ventral telencephalon

Wright, AG, Demyanenko, GP, Powell, A, Schachner, M, Enriquez-Barreto, L, Tran, TS, Polleux, F, Maness, PF

J Neurosci 2007
Participants
Input
Output
Orthologous Events
CHL1 interacts with NRP1 (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-27)
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