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Ncoa1 [nucleoplasm]
Stable Identifier
R-MMU-442496
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
NCOA1, P70365
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Cytoprotection by HMOX1 (Mus musculus)
Fatty acid ligands activate PPARA (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
PPARA:RXRA Coactivator complex [nucleoplasm] (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP7A1 7-hydroxylates CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
CYP7B1 7-hydroxylates 25OH-CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Recycling of bile acids and salts (Mus musculus)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
CYP7B1 7-hydroxylates 25OH-CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Mus musculus)
27-hydroxycholesterol is 7alpha-hydroxylated (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
CYP7A1 7-hydroxylates CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Regulation of lipid metabolism by PPARalpha (Mus musculus)
Fatty acid ligands activate PPARA (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
PPARA:RXRA Coactivator complex [nucleoplasm] (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of transcription cofactors (Mus musculus)
SUMOylation of NCOA1 with SUMO1 (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Estrogen-dependent gene expression (Mus musculus)
HATs and coactivators are recruited to the CTSD gene (Mus musculus)
CTSD gene:ESR1:ESTG:SP1:USF1:USF2:NCOA:EP300:MED1 [nucleoplasm] (Mus musculus)
NCOAs [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NCOAs [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Histone acetyltransferases are recruited to the TFF1 gene (Mus musculus)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Mus musculus)
histone acetyltransferases [nucleoplasm] (Mus musculus)
NCOA1,NCOA3 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
histone acetyltransferases [nucleoplasm] (Mus musculus)
NCOA1,NCOA3 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NCOA1 binds ESR1:estrogen:TGFA gene (Mus musculus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NCOA1 recruits EP300 to TGFA promoter (Mus musculus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
ESR1:estrogen:TFGA gene:NCOA1:EP300 [nucleoplasm] (Mus musculus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NR1H2 and NR1H3-mediated signaling (Mus musculus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Mus musculus)
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Mus musculus)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NCOA1 recruits EP300 to the ABCA1 promoter (Mus musculus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
Ncoa1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P70365 Ncoa1
Gene Names
Ncoa1, Src1
Chain
initiator methionine:, chain:2-1447
Reference Genes
BioGPS Gene:17977 Ncoa1
KEGG:mmu:17977 Ncoa1
Monarch:17977 Ncoa1
NCBI Gene:17977 Ncoa1
UCSC:P70365 Ncoa1
Reference Transcript
RefSeq:XM_011243841.2 Ncoa1
RefSeq:XM_006515005.3 Ncoa1
RefSeq:XM_006515006.3 Ncoa1
RefSeq:NM_010881.2 Ncoa1
RefSeq:XM_006515007.3 Ncoa1
Other Identifiers
103229_at
10399265
105405_at
106920_at
1418594_a_at
1434515_at
1443397_at
17279805
17977
4394598
4406557
4518007
4526693
4529899
4608689
4626437
4676502
4698306
4703610
4727095
4734920
4745213
4762036
4769828
4798210
4822172
4856752
4866647
4901899
4904076
4927780
4962141
4967304
4969169
4982940
4997797
5006237
5015774
5113141
5116969
5165692
5185922
5206362
5243757
5273827
5296081
5357344
5378616
5396465
5399027
5452461
5523078
5551325
A_51_P502888
A_55_P2077438
A_55_P2130975
A_55_P2729858
A_66_P126138
A_66_P130582
GE42649
GO:0000435
GO:0000785
GO:0000977
GO:0002155
GO:0003677
GO:0003682
GO:0003713
GO:0003824
GO:0004402
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005829
GO:0005886
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0007595
GO:0008584
GO:0009725
GO:0016071
GO:0016740
GO:0016746
GO:0016922
GO:0021549
GO:0021766
GO:0021854
GO:0021987
GO:0022414
GO:0030331
GO:0030374
GO:0030520
GO:0032355
GO:0032526
GO:0032570
GO:0032870
GO:0032991
GO:0035357
GO:0042789
GO:0042974
GO:0043065
GO:0043226
GO:0044849
GO:0044877
GO:0045666
GO:0045893
GO:0045925
GO:0045944
GO:0046965
GO:0046983
GO:0048856
GO:0050847
GO:0060090
GO:0060179
GO:0060713
GO:0061733
GO:0090575
GO:0140096
GO:0140110
GO:1900076
GO:1904017
GO:1904179
ILMN_1257974
ILMN_2719784
mMC009966
mMR030837
u56920_s_at
Participates
as an input of
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Mus musculus)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)
NCOA1 binds ESR1:estrogen:TGFA gene (Mus musculus)
SUMOylation of NCOA1 with SUMO1 (Mus musculus)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Mus musculus)
as a component of
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
as a member of
NCOA1,NCOA3 [nucleoplasm] (Mus musculus)
NCOAs (PPARG,RXRA) [nucleoplasm] (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
as a candidate of
NCOAs [nucleoplasm] (Mus musculus)
Other forms of this molecule
Ncoa1 [nucleoplasm]
Ncoa1 [nucleoplasm]
Ncoa1 [nucleoplasm]
Inferred From
NCOA1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_035011.1
,
XP_006515069.1
,
XP_006515068.1
,
XP_011242143.1
,
XP_006515070.1
ENSEMBL
ENSMUST00000085814
,
ENSMUSP00000082971
,
ENSMUSP00000151716
,
ENSMUST00000217794
,
ENSMUSP00000151358
,
ENSMUST00000220434
PRO
P70365
GlyGen
P70365
MGI
1276523
PDB
5NWX
,
1OJ5
,
5Y7W
,
4DMA
,
2O9I
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