Reactome | FPR2 [plasma membrane]

FPR2 [plasma membrane]

Stable Identifier

R-MMU-416408

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

O88536

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Formyl peptide receptors bind formyl peptides and many other ligands (Mus musculus)
        
        FPR2 binds FPR2 ligands (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)
        
        FPR2:FPR2 ligands [plasma membrane] (Mus musculus)
        
        FPR2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:O88536

Reference Genes

BioGPS Gene:14289

ENSEMBL:ENSMUSG00000052270

KEGG:mmu:14289

Monarch:14289

NCBI Gene:14289

UCSC:O88536

Reference Transcript

RefSeq:NM_008039.2

Other Identifiers

101800_at

1422953_at

14289

17333731

4662906

4941722

4949179

5304840

5329706

5472738

A_51_P288138

A_52_P109378

GE34423

GO:0001540

GO:0002376

GO:0002430

GO:0004875

GO:0004930

GO:0004982

GO:0005886

GO:0006935

GO:0006954

GO:0007165

GO:0007186

GO:0007200

GO:0007204

GO:0016020

GO:0032930

GO:0038023

GO:0050918

GO:1904646

ILMN_1242457

mMC019750

Participates

as a member of

as an input of

FPR2 binds FPR2 ligands (Mus musculus)

as a component of

FPR2:FPR2 ligands [plasma membrane] (Mus musculus)

Other forms of this molecule

FPR2 [ficolin-1-rich granule membrane]

FPR2 [tertiary granule membrane]

FPR2 [specific granule membrane]

FPR3 [plasma membrane]

Inferred From

FPR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032065.1

ENSEMBL

ENSMUSG00000052270, ENSMUST00000064068, ENSMUSP00000065799

PRO

O88536

GlyGen

O88536

MGI

1278319