Reactome | PHC3 [nucleoplasm]

PHC3 [nucleoplasm]

Stable Identifier

R-MMU-389116

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Q8CHP6

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by E2F6 (Mus musculus)
      - E2F6 binds the PRC1 complex (Mus musculus)
        
        E2F6:(TFDP1,TFDP2):PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3) [nucleoplasm] (Mus musculus)
        
        PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3) [nucleoplasm] (Mus musculus)
        
        PHC1,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC3 [nucleoplasm] (Mus musculus)
        
        PRC1 (BMI1,PCGF2:RYBP:RING1:PHC1,PHC3) [nucleoplasm] (Mus musculus)
        
        PHC1,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC3 [nucleoplasm] (Mus musculus)
    - Transcriptional regulation by RUNX1 (Mus musculus)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Mus musculus)
        
        RUNX1 binds PRC1 complexes (Mus musculus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC3 [nucleoplasm] (Mus musculus)
        
        RUNX1:CBFB:(PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC3 [nucleoplasm] (Mus musculus)

Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - PTEN Regulation (Mus musculus)
      - Regulation of PTEN gene transcription (Mus musculus)
        
        MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Mus musculus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Mus musculus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Mus musculus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC3 [nucleoplasm] (Mus musculus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC3 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8CHP6 Phc3

Gene Names

Phc3

Chain

chain:1-981

Reference Genes

BioGPS Gene:241915 Phc3

KEGG:mmu:241915 Phc3

Monarch:241915 Phc3

NCBI Gene:241915 Phc3

UCSC:Q8CHP6 Phc3

Reference Transcript

Other Identifiers

10497646

10497648

1443651_at

1455312_at

164219_at

17404548

241915

4466793

4604821

4611287

4611374

4725367

4792050

4811199

4847177

4891108

4892069

4900674

4902729

4978992

4983357

5053164

5061658

5104348

5129781

5152417

5162399

5241476

5350027

5373093

5415048

5421849

5473559

5500140

5501244

5579928

5609675

5613804

A_51_P305881

A_51_P514014

A_52_P142531

A_52_P413940

A_55_P1985530

A_55_P2127238

A_55_P2718172

A_55_P2795468

A_66_P121818

GE136812

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0008270

GO:0031519

GO:0035102

GO:0042393

GO:0045892

GO:0046872

ILMN_1217850

ILMN_2501512

ILMN_2702360

mMC007973

mMR030559

Participates

as a component of

as a member of

Other forms of this molecule

Phc3 [nucleoplasm]

Inferred From

PHC3 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSG00000037652, ENSMUST00000129817, ENSMUST00000168645, ENSMUSP00000130142, ENSMUSP00000114916

PRO

Q8CHP6

GlyGen

Q8CHP6

MGI

2181434

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