Reactome | Cep76 [cytosol]

Cep76 [cytosol]

Stable Identifier

R-MMU-380281

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

CEP76, Q0VEJ0

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Assembly of the 9+0 primary cilium (Mus musculus)
    - Anchoring of the basal body to the plasma membrane (Mus musculus)
      - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - C2CD3 binds the mother centriole (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - CP110 and CEP97 dissociate from the centriole (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - MARK4 binds ODF2 in the centriole (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - Recruitment of transition zone proteins (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
      - The distal appendage proteins recruit TTBK2 (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Cep76 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q0VEJ0

Gene Names

Cep76

Reference Genes

BioGPS Gene:225659 Cep76

ENSEMBL:ENSMUSG00000073542

KEGG:mmu:225659 Cep76

Monarch:225659 Cep76

NCBI Gene:225659 Cep76

UCSC:Q0VEJ0 Cep76

Reference Transcript

RefSeq:NM_001081073.2 Cep76

Other Identifiers

10459576

1437209_at

1437254_at

17355213

225659

4488162

4505187

4755578

4769137

4774037

4802464

4819241

4828985

4845121

4884890

4901395

5105096

5108853

5153524

5251883

5287075

5472026

A_51_P345316

GE1525562

GO:0003674

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0032991

GO:0043226

GO:0046599

ILMN_1253298

mMC013982

Participates

as a component of

Inferred From

CEP76 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001074542.1

ENSEMBL

ENSMUST00000097542, ENSMUSP00000095149, ENSMUSG00000073542

PRO

Q0VEJ0

MGI

1923401

Cite Us!