Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Cep70 [cytosol]
Stable Identifier
R-MMU-380257
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
CEP70, Q6IQY5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Prometaphase (Mus musculus)
Recruitment of NuMA to mitotic centrosomes (Mus musculus)
Association of NuMA with microtubules (Mus musculus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Translocation of NuMA to the centrosomes (Mus musculus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
AURKA Activation by TPX2 (Mus musculus)
TPX2 binds AURKA at centrosomes (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
TPX2 promotes AURKA autophosphorylation (Mus musculus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome maturation (Mus musculus)
Loss of proteins required for interphase microtubule organization from the centrosome (Mus musculus)
Loss of C-Nap-1 from centrosomes (Mus musculus)
cNAP-1 depleted centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Loss of Nlp from mitotic centrosomes (Mus musculus)
Dissociation of Phospho-Nlp from the centrosome (Mus musculus)
Nlp-depleted centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Plk1-mediated phosphorylation of Nlp (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Recruitment of mitotic centrosome proteins and complexes (Mus musculus)
Recruitment of CDK11p58 to the centrosomes (Mus musculus)
Centrosomes containing recruited CDK11p58 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Recruitment of Plk1 to centrosomes (Mus musculus)
Centrosome associated Plk1 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Regulation of PLK1 Activity at G2/M Transition (Mus musculus)
AJUBA binds centrosome-associated AURKA (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:AURKA:AJUBA [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
AJUBA facilitates AURKA autophosphorylation (Mus musculus)
Centrosome:AURKA:AJUBA [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
AURKA phosphorylates PLK1 (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
BORA binds PLK1 and AURKA (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Organelle biogenesis and maintenance (Mus musculus)
Cilium Assembly (Mus musculus)
Assembly of the 9+0 primary cilium (Mus musculus)
Anchoring of the basal body to the plasma membrane (Mus musculus)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
C2CD3 binds the mother centriole (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
CP110 and CEP97 dissociate from the centriole (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
MARK4 binds ODF2 in the centriole (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Recruitment of transition zone proteins (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
The distal appendage proteins recruit TTBK2 (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Cep70 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q6IQY5
Gene Names
Cep70
Reference Genes
BioGPS Gene:68121 Cep70
ENSEMBL:ENSMUSG00000056267
KEGG:mmu:68121 Cep70
Monarch:68121 Cep70
NCBI Gene:68121 Cep70
UCSC:Q6IQY5 Cep70
Reference Transcript
RefSeq:XM_030244533.2 Cep70
RefSeq:XM_030244536.2 Cep70
RefSeq:XM_030244534.2 Cep70
RefSeq:NM_023873.5 Cep70
RefSeq:XM_030244535.2 Cep70
Other Identifiers
10588091
115417_at
1422653_at
1430231_a_at
17520687
4320665
4396020
4397866
4422519
4529114
4529833
4631867
4635272
4682564
4709473
4746293
4808654
4814974
4859394
4880332
4901610
4956246
4999355
5157809
5158764
5179558
5217003
5249736
5286597
5309043
5320718
5399401
5399459
5463237
5487773
5606847
5610554
5615230
68121
A_51_P276831
A_52_P198780
A_52_P329054
GE41478
GO:0003674
GO:0005515
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0008092
GO:0008150
GO:0042802
GO:0043015
GO:0044782
GO:0060271
GO:0070507
ILMN_1234688
ILMN_1259385
mMC001075
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Nlp-depleted centrosome [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
cNAP-1 depleted centrosome [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Inferred From
CEP70 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_030100396.1
,
XP_030100393.1
,
XP_030100394.1
,
NP_076362.2
,
XP_030100395.1
ENSEMBL
ENSMUSP00000091312
,
ENSMUST00000093795
,
ENSMUSG00000056267
,
ENSMUST00000191335
,
ENSMUSP00000139816
PRO
Q6IQY5
MGI
1915371
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
