Reactome | Agt [extracellular region]

Agt [extracellular region]

Stable Identifier

R-MMU-374187

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

AGT(25-32), P11859

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P11859 Agt

Gene Names

Agt, Serpina8

Chain

signal peptide:1-24, chain:25-477, peptide:25-34, peptide:25-33, peptide:25-32, peptide:25-31, peptide:25-29, peptide:25-28, peptide:26-32, peptide:27-32

Reference Genes

UCSC:P11859 Agt

Participates

as an input of

ENPEP:Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(26-32) (Angiotensin-(2-8)) (Mus musculus)
ACE2(18-805):Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(25-31) (Angiotensin-(1-7)) (Mus musculus)
AGT(25-32) binds to AGTR2 (Mus musculus)
AGT(25-32) binds to AGTR1 (Mus musculus)

as an output of

Cathepsin G hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) (Mus musculus)
Cathepsin Z (Cathepsin X) hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) (Mus musculus)
Chymase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) (Mus musculus)
ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) (Mus musculus)
Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) (Mus musculus)

as a member of

Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)

as a component of

AGTR1:AGT(25-32) [plasma membrane] (Mus musculus)
AGTR2:AGT(25-32) [plasma membrane] (Mus musculus)

Other forms of this molecule

Agt [extracellular region]

Agt(29-35) [extracellular region]

Agt [extracellular region]

Inferred From

AGT(25-32) [extracellular region] (Homo sapiens)

Cross References

PRO

P11859

GlyGen

P11859

MGI

87963

PDB

2WY0, 2WXY, 2WXX