Reactome | Tcf7 [nucleoplasm]

Tcf7 [nucleoplasm]

Stable Identifier

R-MMU-3299543

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

TCF7, Q00417

Locations in the PathwayBrowser

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Developmental Biology (Mus musculus)

- MITF-M-regulated melanocyte development (Mus musculus)
  - MITF-M-dependent gene expression (Mus musculus)
    - Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Mus musculus)
      - HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Mus musculus)
        
        HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Mus musculus)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Mus musculus)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Mus musculus)
        
        TCF/LEF [nucleoplasm] (Mus musculus)
        
        Tcf7 [nucleoplasm] (Mus musculus)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Mus musculus)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Mus musculus)
        
        TCF/LEF [nucleoplasm] (Mus musculus)
        
        Tcf7 [nucleoplasm] (Mus musculus)

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional regulation by RUNX3 (Mus musculus)
      - RUNX3 regulates WNT signaling (Mus musculus)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Mus musculus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        Tcf7 [nucleoplasm] (Mus musculus)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        Tcf7 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q00417 Tcf7

Gene Names

Tcf7, Tcf-1, Tcf1

Chain

chain:1-419

Reference Genes

BioGPS Gene:21414 Tcf7

KEGG:mmu:21414 Tcf7

Monarch:21414 Tcf7

NCBI Gene:21414 Tcf7

UCSC:Q00417 Tcf7

Reference Transcript

Other Identifiers

10385776

1433471_at

1450461_at

17262600

21414

4328421

4340655

4349744

4462139

4473127

4637435

4683127

4795187

4886211

4964705

4993324

5028709

5114944

5141478

5174853

5264134

5296197

5386537

5389154

5409122

5458125

5481940

97994_at

97995_at

A_52_P244702

A_52_P244711

A_55_P2109633

A_65_P06324

GE33773

GO:0000122

GO:0000785

GO:0000791

GO:0000976

GO:0000978

GO:0000981

GO:0001217

GO:0001227

GO:0002376

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0006310

GO:0006355

GO:0006357

GO:0008013

GO:0009888

GO:0016055

GO:0016604

GO:0021915

GO:0030154

GO:0030538

GO:0033153

GO:0042127

GO:0042492

GO:0043066

GO:0044336

GO:0045586

GO:0046632

GO:0048557

GO:0048619

GO:0048856

GO:0060070

GO:0071353

GO:1990837

GO:1990907

ILMN_1242308

ILMN_2661648

ILMN_2717975

X61385_s_at

mMC010149

Participates

as a member of

TCF/LEF [nucleoplasm] (Mus musculus)

as a candidate of

Other forms of this molecule

Tcf7 [nucleoplasm]

Inferred From

TCF7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_033357.1, NP_001300910.2

ENSEMBL

ENSMUSG00000000782, ENSMUST00000086844, ENSMUSP00000084055

PRO

Q00417

MGI

98507

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