Reactome | MAPKAP1 [cytosol]

MAPKAP1 [cytosol]

Stable Identifier

R-MMU-3006620

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q8BKH7

Locations in the PathwayBrowser

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Cellular responses to stimuli (Mus musculus)

- Cellular responses to mechanical stimuli (Mus musculus)
  - Response of endothelial cells to shear stress (Mus musculus)
    - High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Mus musculus)
      - mTORC2 phosphorylates AKT1 on serine-473 (Mus musculus)
        
        mTORC2:PIP3 [plasma membrane] (Mus musculus)
        
        MAPKAP1:PIP3 [plasma membrane] (Mus musculus)
        
        MAPKAP1 [cytosol] (Mus musculus)

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Expression and Degradation (Mus musculus)
        
        Regulation of TP53 Degradation (Mus musculus)
        
        mTORC2 phosphorylates SGK1 (Mus musculus)
        
        mTORC2:PIP3 [plasma membrane] (Mus musculus)
        
        MAPKAP1:PIP3 [plasma membrane] (Mus musculus)
        
        MAPKAP1 [cytosol] (Mus musculus)

Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Regulation of T cell activation by CD28 family (Mus musculus)
    - Co-stimulation by CD28 (Mus musculus)
      - CD28 dependent PI3K/Akt signaling (Mus musculus)
        
        mTORC2 phosphorylates AKT at S473 (Mus musculus)
        
        mTORC2:PIP3 [plasma membrane] (Mus musculus)
        
        MAPKAP1:PIP3 [plasma membrane] (Mus musculus)
        
        MAPKAP1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BKH7

Reference Genes

BioGPS Gene:227743

ENSEMBL:ENSMUSG00000038696

KEGG:mmu:227743

Monarch:227743

NCBI Gene:227743

UCSC:Q8BKH7

Reference Transcript

Other Identifiers

10471571

109603_at

112459_at

1417284_at

1427212_at

17370079

227743

4313543

4355186

4364452

4387147

4516933

4575169

4598342

4620158

4656997

4663958

4749206

4871541

4927511

4933310

5052679

5105953

5213466

5320310

5335545

5365879

5373534

5381094

5420003

5514665

A_51_P138876

A_51_P298514

A_52_P278248

A_55_P2046363

A_55_P2046368

GE127438

GE1483057

GO:0000139

GO:0005515

GO:0005546

GO:0005547

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005741

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005770

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0005886

GO:0005929

GO:0006511

GO:0007010

GO:0008286

GO:0016020

GO:0019901

GO:0030307

GO:0031267

GO:0031669

GO:0031901

GO:0031902

GO:0031932

GO:0032869

GO:0033138

GO:0038203

GO:0043066

GO:0043226

GO:0043325

GO:0043491

GO:0046580

GO:0046627

GO:0048471

GO:0051897

GO:0060090

GO:0070300

GO:0080025

GO:0140767

GO:1900407

GO:1902554

ILMN_1233617

ILMN_1241349

ILMN_1256745

ILMN_2659025

ILMN_2739782

mMC002972

mMR030773

Participates

as a component of

MAPKAP1:PIP3 [plasma membrane] (Mus musculus)

Inferred From

MAPKAP1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001277555.1, NP_796319.1, NP_001349849.1, XP_030105858.1, XP_030105844.1, XP_030105859.1, XP_030105857.1, XP_036016792.1, XP_006498038.1, XP_006498046.1, XP_006498041.1, NP_001349850.1, XP_036016785.1, NP_001349848.1, XP_030105839.1, XP_030105861.1, NP_001277554.1, XP_011237385.1, XP_011237386.1

ENSEMBL

ENSMUSP00000116494, ENSMUST00000113123, ENSMUST00000113124, ENSMUSG00000038696, ENSMUSP00000108751, ENSMUSP00000108749, ENSMUST00000147337, ENSMUSP00000108748, ENSMUST00000113126

PRO

Q8BKH7

MGI

2444554