Reactome | PPP3CA [nucleoplasm]

PPP3CA [nucleoplasm]

Stable Identifier

R-MMU-2685599

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

P63328

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Innate Immune System (Mus musculus)
  - C-type lectin receptors (CLRs) (Mus musculus)
    - CLEC7A (Dectin-1) signaling (Mus musculus)
      - CLEC7A (Dectin-1) induces NFAT activation (Mus musculus)
        
        Translocation of CaN:CaM:NFAT to nucleus (Mus musculus)
        
        NFAT:CaN:CaM [nucleoplasm] (Mus musculus)
        
        CaN:CaM:Ca2+ [nucleoplasm] (Mus musculus)
        
        CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm] (Mus musculus)
        
        CaN catalytic alpha/beta:Zn++:Fe3+ [nucleoplasm] (Mus musculus)
        
        CaN-catalytic alpha/beta chains [nucleoplasm] (Mus musculus)
        
        PPP3CA [nucleoplasm] (Mus musculus)
  - Fc epsilon receptor (FCERI) signaling (Mus musculus)
    - FCERI mediated Ca+2 mobilization (Mus musculus)
      - Translocation of CaN:CaM:NFAT to nucleus (Mus musculus)
        
        NFAT:CaN:CaM [nucleoplasm] (Mus musculus)
        
        CaN:CaM:Ca2+ [nucleoplasm] (Mus musculus)
        
        CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm] (Mus musculus)
        
        CaN catalytic alpha/beta:Zn++:Fe3+ [nucleoplasm] (Mus musculus)
        
        CaN-catalytic alpha/beta chains [nucleoplasm] (Mus musculus)
        
        PPP3CA [nucleoplasm] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by WNT (Mus musculus)
  - Beta-catenin independent WNT signaling (Mus musculus)
    - Ca2+ pathway (Mus musculus)
      - Translocation of NFATC1:CaN:CaM to nucleus (Mus musculus)
        
        NFATC1:CaN:CaM [nucleoplasm] (Mus musculus)
        
        CaN:CaM:Ca2+ [nucleoplasm] (Mus musculus)
        
        CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm] (Mus musculus)
        
        CaN catalytic alpha/beta:Zn++:Fe3+ [nucleoplasm] (Mus musculus)
        
        CaN-catalytic alpha/beta chains [nucleoplasm] (Mus musculus)
        
        PPP3CA [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P63328 Ppp3ca

Gene Names

Ppp3ca, Calna

Chain

initiator methionine:1, chain:2-521

Reference Genes

BioGPS Gene:19055 Ppp3ca

KEGG:mmu:19055 Ppp3ca

Monarch:19055 Ppp3ca

NCBI Gene:19055 Ppp3ca

UCSC:P63328 Ppp3ca

Reference Transcript

Other Identifiers

10496338

111216_at

112874_at

1426401_at

1438478_a_at

1452056_s_at

163643_i_at

17402953

19055

4344961

4366227

4420404

4507000

4543586

4573207

4611626

4641652

4697110

4710171

4710496

4775274

4851830

4859179

4890443

4922743

4951976

4972545

4996590

5048045

5051552

5089700

5108164

5198999

5228495

5239058

5249198

5306697

5390356

5398791

5492889

5506541

5532566

5539043

5541873

5561488

95092_at

A_55_P1952738

GE32931

GO:0000082

GO:0003012

GO:0003014

GO:0003824

GO:0004721

GO:0004722

GO:0004723

GO:0005515

GO:0005516

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0005886

GO:0005955

GO:0006355

GO:0006470

GO:0006606

GO:0006816

GO:0006886

GO:0006913

GO:0008287

GO:0008544

GO:0009898

GO:0010613

GO:0010628

GO:0010629

GO:0014883

GO:0014898

GO:0016020

GO:0016787

GO:0019722

GO:0019899

GO:0023057

GO:0030018

GO:0030154

GO:0030163

GO:0030216

GO:0030335

GO:0033173

GO:0033192

GO:0033555

GO:0042104

GO:0042383

GO:0042995

GO:0043161

GO:0043197

GO:0045202

GO:0045669

GO:0045672

GO:0045785

GO:0045807

GO:0045944

GO:0046872

GO:0046878

GO:0046983

GO:0048741

GO:0048813

GO:0048856

GO:0050774

GO:0050804

GO:0051117

GO:0051592

GO:0060079

GO:0061006

GO:0070294

GO:0070886

GO:0090193

GO:0097205

GO:0097720

GO:0098685

GO:0098978

GO:0099170

GO:0110062

GO:0110063

GO:0140096

GO:1903244

GO:1905205

GO:1905665

GO:1905949

ILMN_1227899

ILMN_2486438

ILMN_2611431

ILMN_2971286

j05479_s_at

mMC008508

mMR028696

Participates

as a member of

CaN-catalytic alpha/beta chains [nucleoplasm] (Mus musculus)

Other forms of this molecule

Ppp3ca [cytosol]

Inferred From

PPP3CA [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_032939.1, NP_001280551.1

ENSEMBL

ENSMUST00000070198, ENSMUSP00000053101, ENSMUST00000056758, ENSMUSG00000028161, ENSMUSP00000071040

IntEnz

3.1.3.16

PRO

P63328

GlyGen

P63328

MGI

107164

PDB

9CHU, 9CHV, 4ORB, 9CHX

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62108 Dlg4	3	SAP-90 [plasma membrane] (R-MMU-443606) Dlg4 [endocytic vesicle membrane] (R-MMU-416847) Dlg4 [cytosol] (R-MMU-6794267)	0.527	3
UniProt:P35438 Grin1	3	Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.462	2

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