Reactome | Psen1(299-467) [plasma membrane]

Psen1(299-467) [plasma membrane]

Stable Identifier

R-MMU-2534227

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Presenilin-1 CTF subunit, Psen1 C-terminal fragment

Locations in the PathwayBrowser

Expand all

Developmental Biology (Mus musculus)

- Nervous system development (Mus musculus)
  - Axon guidance (Mus musculus)
    - EPH-Ephrin signaling (Mus musculus)
      - EPH-ephrin mediated repulsion of cells (Mus musculus)
        
        gamma-secretase cleaves EPHB2 (Mus musculus)
        
        gamma-secretase complex [plasma membrane] (Mus musculus)
        
        Presenilin [plasma membrane] (Mus musculus)
        
        Ps1 [plasma membrane] (Mus musculus)
        
        Psen1(299-467) [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P49769 Psen1

Gene Names

Psen1, Ad3h, Psnl1

Chain

chain:1-298, chain:299-467, chain:346-467

Reference Genes

BioGPS Gene:19164 Psen1

KEGG:mmu:19164 Psen1

Monarch:19164 Psen1

NCBI Gene:19164 Psen1

UCSC:P49769 Psen1

Reference Transcript

RefSeq:NM_001362271.1 Psen1

Other Identifiers

102201_s_at

10397094

1421853_at

1425549_at

1450399_at

17277084

19164

4323000

4327985

4363162

4406163

4578637

4583372

4587889

4597139

4698077

4733325

4737776

4984886

5122432

5246920

5264523

5304797

5311646

5419090

5446964

5495672

5506715

5534579

5594185

5594774

A_51_P464576

GE34275

GO:0000045

GO:0000122

GO:0000139

GO:0000776

GO:0001568

GO:0001708

GO:0001756

GO:0001764

GO:0001921

GO:0001947

GO:0002038

GO:0002244

GO:0002265

GO:0002286

GO:0002376

GO:0002573

GO:0003407

GO:0004175

GO:0004190

GO:0005262

GO:0005515

GO:0005634

GO:0005640

GO:0005654

GO:0005737

GO:0005739

GO:0005743

GO:0005765

GO:0005768

GO:0005769

GO:0005783

GO:0005789

GO:0005790

GO:0005791

GO:0005794

GO:0005813

GO:0005815

GO:0005886

GO:0005938

GO:0006355

GO:0006486

GO:0006508

GO:0006509

GO:0006839

GO:0006874

GO:0006914

GO:0006915

GO:0006974

GO:0006979

GO:0007155

GO:0007219

GO:0007220

GO:0007420

GO:0007507

GO:0007611

GO:0007613

GO:0008013

GO:0008021

GO:0008233

GO:0009791

GO:0009986

GO:0010467

GO:0010468

GO:0010628

GO:0010629

GO:0010975

GO:0012505

GO:0015031

GO:0015871

GO:0016020

GO:0016080

GO:0016235

GO:0016485

GO:0016787

GO:0021549

GO:0021795

GO:0021870

GO:0021904

GO:0021987

GO:0022008

GO:0030054

GO:0030154

GO:0030165

GO:0030182

GO:0030326

GO:0030424

GO:0030425

GO:0030426

GO:0030900

GO:0031410

GO:0031594

GO:0031901

GO:0031965

GO:0032436

GO:0032469

GO:0032760

GO:0032991

GO:0034205

GO:0034330

GO:0035253

GO:0035282

GO:0035556

GO:0040011

GO:0042059

GO:0042307

GO:0042383

GO:0042500

GO:0042734

GO:0042982

GO:0042987

GO:0042995

GO:0043005

GO:0043011

GO:0043025

GO:0043065

GO:0043066

GO:0043198

GO:0043226

GO:0043524

GO:0043589

GO:0045121

GO:0045202

GO:0045296

GO:0045821

GO:0045893

GO:0048143

GO:0048167

GO:0048538

GO:0048666

GO:0048705

GO:0048854

GO:0048856

GO:0048870

GO:0050435

GO:0050673

GO:0050771

GO:0050808

GO:0050820

GO:0050852

GO:0050877

GO:0051117

GO:0051208

GO:0051402

GO:0051563

GO:0051604

GO:0051966

GO:0055074

GO:0055085

GO:0060075

GO:0060291

GO:0060828

GO:0060999

GO:0070050

GO:0070588

GO:0070765

GO:0070851

GO:0097060

GO:0097190

GO:0098609

GO:0098693

GO:0098712

GO:0098794

GO:0098978

GO:0099175

GO:0140249

GO:1904646

GO:1905908

GO:1990535

GO:2000059

GO:2001234

ILMN_1214811

ILMN_1257180

ILMN_2718112

ILMN_2761689

Msa.43187.0_s_at

af007560-2_at

af007560-2_g_at

mMC022002

Participates

as a member of

Azurophil granule membrane proteins [plasma membrane] (Mus musculus)

as a component of

Other forms of this molecule

Psen1 [azurophil granule membrane]

Psen1 [plasma membrane]

Psen1 [azurophil granule membrane]

Psen1(1-298) [plasma membrane]

Psen1 N-term fragment [plasma membrane]

Inferred From

PSEN1(299-467) [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001349200.1

ENSEMBL

ENSMUST00000041806, ENSMUSP00000048363, ENSMUST00000101225, ENSMUSP00000098786, ENSMUSG00000019969

PRO

P49769

MGI

1202717

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46096	6	SYT1 [clathrin-sculpted monoamine transport vesicle membrane] (R-MMU-372508) SYT1 [plasma membrane] (R-MMU-168786) SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-MMU-917741) SYT1 [clathrin-sculpted glutamate transport vesicle membrane] (R-MMU-372514) SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane] (R-MMU-210536) SYT1 [clathrin-coated endocytic vesicle membrane] (R-MMU-8869113)	0.571	6
UniProt:P35438 Grin1	3	Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.564	3
UniProt:P14211 Calr	8	Calreticulin [phagocytic vesicle] (R-MMU-1236838) CALR [phagocytic vesicle membrane] (R-MMU-1236879) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-MMU-8863866) Calreticulin [extracellular region] (R-MMU-3221763) CALR [endocytic vesicle lumen] (R-MMU-2239448) CALR [extracellular region] (R-MMU-2197641) CALR [endoplasmic reticulum lumen] (R-MMU-195905) CALR [lumenal side of endoplasmic reticulum membrane] (R-MMU-985502)	0.463	3

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