Netrins are a family of extracellular proteins that include axonal guidance factors. Their N-terminal domains are homologous to the LN domains of laminins. Netrin-4 (but not other forms) can bind laminin gamma-1 and gamma-3 short arms in basement membrane, suggesting a role in regulating basement membrane formation (Schneiders et al. 2007). Netrin-4 has been found associated in a functional complex with laminin gamma-1 chain and integrin alpha6beta1, suggesting a role in regulation of neurogenesis in the olfactory system (Staquicini et al. 2009).