Reactome | phospho-Lat [plasma membrane]

phospho-Lat [plasma membrane]

Stable Identifier

R-MMU-2396597

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-5Y-LAT-2, O54957

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O54957

Gene Names

Lat

Reference Genes

BioGPS Gene:16797 Lat

ENSEMBL:ENSMUSG00000030742

ENSEMBL:ENSMUSG00000030742.8 Lat

KEGG Gene (Mus musculus):16797 Lat

Monarch:16797 Lat

NCBI Gene:16797 Lat

UCSC:O54957 Lat

Reference Transcript

RefSeq:NM_010689.3 Lat

Other Identifiers

102228_at

10567825

1460651_at

16797

17496150

4311182

4347579

4533540

4602912

4652618

4669415

4704393

4746859

4757751

4989236

5080860

5284332

5400377

5502421

GE35671

GO:0001772

GO:0002250

GO:0002260

GO:0002376

GO:0005515

GO:0005634

GO:0005794

GO:0005886

GO:0005911

GO:0006954

GO:0006955

GO:0006968

GO:0007165

GO:0007169

GO:0007229

GO:0007265

GO:0008180

GO:0010467

GO:0016020

GO:0016192

GO:0019722

GO:0019901

GO:0023052

GO:0030159

GO:0035556

GO:0043226

GO:0043303

GO:0048872

GO:0050852

GO:0050863

GO:0060090

ILMN_2660551

mMC016008

Participates

as an output of

as an input of

Recruitment of GRB2:SOS to p-5Y-LAT (Mus musculus)

as a component of

p-5Y-LAT:p-SHC1:GRB2:SOS1 [plasma membrane] (Mus musculus)

Other forms of this molecule

phospho-Lat [plasma membrane]

Lat [plasma membrane]

phospho-Lat [plasma membrane]

Inferred From

p-5Y-LAT-2 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 127 (in Homo sapiens)

Coordinate

127

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 132 (in Homo sapiens)

Coordinate

132

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 171 (in Homo sapiens)

Coordinate

171

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 191 (in Homo sapiens)

Coordinate

191

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 226 (in Homo sapiens)

Coordinate

226

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_034819.1

Ensembl

ENSMUSG00000030742, ENSMUST00000032997, ENSMUSP00000032997

PRO

O54957

MGI

1342293

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62077 Plcg1	10	p-Y-Plcg1 [cytosol] (R-MMU-9029083) Plcg1 [cytosol] (R-MMU-9638030) p-4Y-Plcg1 [plasma membrane] (R-MMU-9030452) phospho-p-Y771,Y783-PLCG1 [plasma membrane] (R-MMU-1169084) phospho-p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-MMU-202357) PLCG1 [plasma membrane] (R-MMU-167682) P-Plcg1 [cytosol] (R-MMU-1251936) Plcg1 [plasma membrane] (R-MMU-1251925) PLCG1 [cytosol] (R-MMU-202320) phospho-p-4Y-PLCG1 [plasma membrane] (R-MMU-167679)	0.669	5
UniProt:Q60631 Grb2	3	Grb2 [cytosol] (R-MMU-74686) Grb2 [plasma membrane] (R-MMU-202993) Grb2 [cytosol] (R-MMU-443287)	0.669	5
UniProt:Q60787 Lcp2	2	SLP-76 [cytosol] (R-MMU-430203) phospho-Lcp2 [cytosol] (R-MMU-202175)	0.564	8
UniProt:Q8BGW0 THMS1			0.527	4
UniProt:Q3TTA7	1	CBLB [cytosol] (R-MMU-976009)	0.527	7
UniProt:Q9WTK7	2	STK11 [nucleoplasm] (R-MMU-164119) STK11 [cytosol] (R-MMU-380954)	0.463	2

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