Reactome | Col8a2 [extracellular region]

Col8a2 [extracellular region]

Stable Identifier

R-MMU-2192745

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

3x4Hyp-3Hyp-GalHyl-COL8A2, P25318

Locations in the PathwayBrowser

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Extracellular matrix organization (Mus musculus)

- Collagen formation (Mus musculus)
  - Assembly of collagen fibrils and other multimeric structures (Mus musculus)
    - Formation of collagen networks (Mus musculus)
      - Collagen networks [extracellular region] (Mus musculus)
        
        Collagen type VIII fibril [extracellular region] (Mus musculus)
        
        Tropocollagen type VIII [extracellular region] (Mus musculus)
        
        Col8a2 [extracellular region] (Mus musculus)
      - Network forming tropocollagens [extracellular region] (Mus musculus)
        
        Tropocollagen type VIII [extracellular region] (Mus musculus)
        
        Col8a2 [extracellular region] (Mus musculus)
  - Collagen biosynthesis and modifying enzymes (Mus musculus)
    - Secretion of collagens (Mus musculus)
      - Collagens and tropocollagens [extracellular region] (Mus musculus)
        
        Non-fibrillar collagens [extracellular region] (Mus musculus)
        
        Tropocollagen type VIII [extracellular region] (Mus musculus)
        
        Col8a2 [extracellular region] (Mus musculus)
- Degradation of the extracellular matrix (Mus musculus)
  - Collagen degradation (Mus musculus)
    - Collagen type VIII degradation by MMP1 (Mus musculus)
      - Collagen type VIII fibril [extracellular region] (Mus musculus)
        
        Tropocollagen type VIII [extracellular region] (Mus musculus)
        
        Col8a2 [extracellular region] (Mus musculus)
- Integrin cell surface interactions (Mus musculus)
  - Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Mus musculus)
    - Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Mus musculus)
      - Collagen type VIII fibril [extracellular region] (Mus musculus)
        
        Tropocollagen type VIII [extracellular region] (Mus musculus)
        
        Col8a2 [extracellular region] (Mus musculus)
    - Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Mus musculus)
      - Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Mus musculus)
        
        Collagen type VIII fibril [extracellular region] (Mus musculus)
        
        Tropocollagen type VIII [extracellular region] (Mus musculus)
        
        Col8a2 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:P25318

Gene Names

Col8a2

Reference Genes

BioGPS Gene:329941 Col8a2

ENSEMBL:ENSMUSG00000056174

KEGG:mmu:329941 Col8a2

Monarch:329941 Col8a2

NCBI Gene:329941 Col8a2

UCSC:P25318 Col8a2

Reference Transcript

RefSeq:NM_199473.3 Col8a2

Other Identifiers

10508142

112509_at

1434667_at

17418581

329941

4385349

4403304

4438236

4471429

4480296

4546188

4564821

4603203

4633321

4635598

4666808

4669846

4675346

4786438

4857789

4953334

4998291

5004434

5066860

5216480

5244235

5408965

5518958

A_52_P302544

A_55_P1960631

A_66_P134043

GE1532722

GO:0001525

GO:0001935

GO:0005198

GO:0005515

GO:0005576

GO:0005581

GO:0005604

GO:0007155

GO:0030020

GO:0030312

GO:0031012

GO:0048593

ILMN_2503839

ILMN_2839646

mMC006653

Participates

as a component of

Tropocollagen type VIII [extracellular region] (Mus musculus)

Other forms of this molecule

Col8a2 [endoplasmic reticulum lumen]

Col8a2 [extracellular region]

Col8a2 [endoplasmic reticulum lumen]

Inferred From

Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)

3x4Hyp-3Hyp-GalHyl-COL8A2 [extracellular region] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,3S)-3-hydroxyproline at unknown position

PsiMod Name

(2S,3S)-3-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.

Name

O5-galactosyl-L-hydroxylysine at unknown position

PsiMod Name

O5-galactosyl-L-hydroxylysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.

Cross References

RefSeq

NP_955767.1

ENSEMBL

ENSMUST00000070132, ENSMUSG00000056174, ENSMUSP00000070270

PRO

P25318

MGI

88464