Reactome | H2-M5 [plasma membrane]

H2-M5 [plasma membrane]

Stable Identifier

R-MMU-197572

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

HLA class I histocompatibility antigen, alpha chain F precursor, A7VMS3

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Class I MHC mediated antigen processing & presentation (Mus musculus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
      - Expression of peptide bound class I MHC on cell surface (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)
    - Antigen processing-Cross presentation (Mus musculus)
      - ER-Phagosome pathway (Mus musculus)
        
        Export of peptide loaded MHC class I complex to PM (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)
      - Endosomal/Vacuolar pathway (Mus musculus)
        
        Translocation of peptide bound MHC class I complex to cell surface (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)
  - Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Mus musculus)
    - MHC Class I interacts with CD160 (Mus musculus)
      - MHC Class I interacting with CD160 [plasma membrane] (Mus musculus)
        
        MHC Class I molecules interacting with CD160 [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)
      - MHC Class I molecules interacting with CD160 [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)
    - TCR complex interacts with peptide antigen-presenting MHC Class I (Mus musculus)
      - Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)
      - TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-M5 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:A7VMS3

Gene Names

H2-M5

Reference Genes

BioGPS Gene:240095 H2-M5

CTD Gene:240095 H2-M5

ENSEMBL:ENSMUSG00000024459

KEGG:mmu:240095 H2-M5

Monarch:240095 H2-M5

NCBI Gene:240095 H2-M5

UCSC:A7VMS3 H2-M5

Reference Transcript

RefSeq:NM_001115075.2 H2-M5

Other Identifiers

10450843

17344811

240095

4406155

4521860

4912677

4950361

4990635

5136964

5139322

5153535

5216688

5392742

5541352

5549548

A_55_P2135074

A_55_P2135079

A_55_P2487779

A_55_P2741144

GO:0001916

GO:0002376

GO:0002474

GO:0002476

GO:0002486

GO:0005102

GO:0005615

GO:0006955

GO:0009897

GO:0016020

GO:0030670

GO:0042605

GO:0042612

GO:0098553

ILMN_1251345

mMC013262

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)

Other forms of this molecule

H2-M5 [early endosome membrane]

H2-M5 [recycling endosome membrane]

H2-M5 [phagocytic vesicle membrane]

H2-M5 [Golgi membrane]

H2-M5 [ER to Golgi transport vesicle membrane]

H2-M5 [secretory granule membrane]

H2-M5 [azurophil granule membrane]

H2-M5 [plasma membrane]

H2-M5 [lumenal side of endoplasmic reticulum membrane]

Inferred From

HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001108547.1

ENSEMBL

ENSMUST00000169189, ENSMUSG00000024459, ENSMUSP00000131365

MGI

95917