Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-Cdc25c [nucleoplasm]
Stable Identifier
R-MMU-156496
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
p-S216-CDC25C, P48967
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G2/M Checkpoints (Mus musculus)
Activation of ATR in response to replication stress (Mus musculus)
Phosphorylation of Cdc25C at Ser 216 by Chk1 (Mus musculus)
phospho-Cdc25c [nucleoplasm] (Mus musculus)
G2/M DNA damage checkpoint (Mus musculus)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Mus musculus)
Phosphorylation of Cdc25C at Ser216 by CHEK2 (Mus musculus)
phospho-Cdc25c [nucleoplasm] (Mus musculus)
p-S216-CDC25C translocates to the cytosol (Mus musculus)
phospho-Cdc25c [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P48967
Gene Names
Cdc25c
Reference Genes
BioGPS Gene:12532 Cdc25c
ENSEMBL:ENSMUSG00000044201
KEGG:mmu:12532 Cdc25c
Monarch:12532 Cdc25c
NCBI Gene:12532 Cdc25c
UCSC:P48967 Cdc25c
Reference Transcript
RefSeq:NM_009860.3 Cdc25c
Other Identifiers
102934_s_at
102935_at
10458195
12532
1422252_a_at
1456077_x_at
17353520
4329632
4390616
4508095
4554597
4587414
4660048
4671498
4705030
4770739
4806655
4864662
4893722
4996712
5052418
5086250
5117359
5137236
5139224
5179509
5181029
5193048
5214461
5223846
5282897
5299902
5308820
5362361
5436699
5498354
5568859
A_51_P279575
A_52_P25599
A_66_P114695
GE35191
GO:0000086
GO:0003824
GO:0004721
GO:0004725
GO:0005515
GO:0005634
GO:0005737
GO:0005758
GO:0006470
GO:0007283
GO:0010971
GO:0016787
GO:0019901
GO:0022414
GO:0043226
GO:0048471
GO:0050699
GO:0051301
GO:0110032
GO:0140096
GO:1902751
ILMN_1252063
ILMN_1253115
ILMN_2637704
ILMN_2733046
mMC014443
u15562_s_at
Participates
as an input of
p-S216-CDC25C translocates to the cytosol (Mus musculus)
as an output of
Phosphorylation of Cdc25C at Ser 216 by Chk1 (Mus musculus)
Phosphorylation of Cdc25C at Ser216 by CHEK2 (Mus musculus)
Other forms of this molecule
phospho-Cdc25c [nucleoplasm]
phospho-Cdc25c [cytosol]
Cdc25c [nucleoplasm]
Cdc25c [cytosol]
phospho-Cdc25c [cytosol]
phospho-Cdc25c [nucleoplasm]
Inferred From
p-S216-CDC25C [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 216 (in Homo sapiens)
Coordinate
216
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_033990.2
ENSEMBL
ENSMUST00000060710
,
ENSMUSP00000055427
PRO
P48967
MGI
88350
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text