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hydroxyPro-HIF-alpha [cytosol]
Stable Identifier
R-MMU-1234106
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
cytosol
Synonyms
HIF-alpha with Hydroxylated Proline, HIF1A, HIF2A, HIF3A with Hydroxyproline
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to hypoxia (Mus musculus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Mus musculus)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Mus musculus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Proteasome proteolyzes ub-HIF-alpha (Mus musculus)
ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Neddylation (Mus musculus)
26S proteasome degrades HIFalpha (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
Participants
members
Epas1 [cytosol]
(Mus musculus)
Hif1a [cytosol]
(Mus musculus)
Hif3a [cytosol]
(Mus musculus)
Participates
as an input of
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Mus musculus)
Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Mus musculus)
as a component of
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Mus musculus)
Inferred From
hydroxyPro-HIF-alpha [cytosol]
(Homo sapiens)
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