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Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane]
Stable Identifier
R-MMU-1112563
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Mus musculus)
Cell junction organization (Mus musculus)
Cell-cell junction organization (Mus musculus)
Adherens junctions interactions (Mus musculus)
Activation of STAT3 by cadherin engagement (Mus musculus)
IL6ST is tyrosine phosphorylated (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST binds STAT3 (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylation of STAT3 by IL6 receptor (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:p-Y705-STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
p-Y705-STAT3 dissociates from IL6 receptor (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:p-Y705-STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-6 family signaling (Mus musculus)
Interleukin-6 signaling (Mus musculus)
IL6ST is tyrosine phosphorylated (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
PTPN11 binds CBL (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11:CBL [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
PTPN11 binds p-Y759-IL6ST (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
PTPN11 is phosphorylated (Mus musculus)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Phosphorylated STATs are released (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
SOCS3 binds IL6ST (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Serine phosphorylation of STATs (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF-independent MAPK1/3 activation (Mus musculus)
MAPK1 (ERK2) activation (Mus musculus)
MAP2K2 binds MAPK1 (Mus musculus)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
MAPK3 (ERK1) activation (Mus musculus)
MAP2K1 binds MAPK3 (Mus musculus)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Activated JAK1, JAK2, TYK2 [cytosol]
(Mus musculus)
phospho-Il6st [plasma membrane]
(Mus musculus)
Participates
as a component of
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Mus musculus)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Mus musculus)
Inferred From
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane]
(Homo sapiens)
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