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CSTF hexamer [nucleoplasm]
Stable Identifier
R-HSA-9970107
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Dengue Virus Infection (Homo sapiens)
Dengue Virus-Host Interactions (Homo sapiens)
NS5 interacts with Spliceosome (Homo sapiens)
NS5:Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Cleavage and Polyadenylation Complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Cleavage and Polyadenylation Complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA 3'-end processing (Homo sapiens)
TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
Cleavage and Polyadenylation Complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
mRNA Polyadenylation (Homo sapiens)
CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
CPA complex components dissociate from polyadenylated pre-mRNA (intronic PAS) (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
CPA complex components dissociate from polyadenylated pre-mRNA (proximal 3'UTR PAS) (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
CPSF3 cleaves pre-mRNA at distal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
CPSF3 cleaves pre-mRNA at proximal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Core CPA complex binds capped pre-mRNA (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Formation of the CSTF complex (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Formation of the core cleavage and polyadenylation complex (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
PP1 dephosphorylates RNA Pol II (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
CPA complex [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
CPA complex [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
RBBP6 activates CPSF complex (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
CPA complex [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Recruitment of other CPA components to pre-mRNA-bound CPA core (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
CPA complex [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
U1 snRNP suppresses CPSF3-mediated pre-mRNA cleavage at intronic PAS (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Ub-K63-CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
CSTF hexamer [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
29186539
Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals
Yang, W
,
Hsu, PL
,
Yang, F
,
Song, JE
,
Varani, G
Nucleic Acids Res
2018
Participants
components
x 2
CSTF heterotrimer [nucleoplasm]
(Homo sapiens)
Participates
as an output of
Formation of the CSTF complex (Homo sapiens)
as an input of
Formation of the core cleavage and polyadenylation complex (Homo sapiens)
as a component of
Core CPA complex [nucleoplasm] (Homo sapiens)
Ub-K63-Core CPA complex [nucleoplasm] (Homo sapiens)
Cleavage and Polyadenylation Complex [nucleoplasm] (Homo sapiens)
Inferred To
CSTF hexamer [nucleoplasm]
(Bos taurus)
CSTF hexamer [nucleoplasm]
(Caenorhabditis elegans)
CSTF hexamer [nucleoplasm]
(Canis familiaris)
CSTF hexamer [nucleoplasm]
(Danio rerio)
CSTF hexamer [nucleoplasm]
(Dictyostelium discoideum)
CSTF hexamer [nucleoplasm]
(Drosophila melanogaster)
CSTF hexamer [nucleoplasm]
(Gallus gallus)
CSTF hexamer [nucleoplasm]
(Mus musculus)
CSTF hexamer [nucleoplasm]
(Plasmodium falciparum)
CSTF hexamer [nucleoplasm]
(Rattus norvegicus)
CSTF hexamer [nucleoplasm]
(Schizosaccharomyces pombe)
CSTF hexamer [nucleoplasm]
(Sus scrofa)
CSTF hexamer [nucleoplasm]
(Xenopus tropicalis)
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