Reactome | OTC G83D trimer [mitochondrial matrix]

OTC G83D trimer [mitochondrial matrix]

Stable Identifier

R-HSA-9958208

Type

Complex

Species

Homo sapiens

Compartment

mitochondrial matrix

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of metabolism (Homo sapiens)
  - Diseases of the urea cycle (Homo sapiens)
    - OTC variants cause OTC deficiency (Homo sapiens)
      - OTC main chain variants cause OTC deficiency (Homo sapiens)
        
        OTC variants don't synthesize L-citrulline (Homo sapiens)
        
        OTC variant trimers [mitochondrial matrix] (Homo sapiens)
        
        other OTC variants [mitochondrial matrix] (Homo sapiens)
        
        OTC G83D trimer [mitochondrial matrix] (Homo sapiens)

General

other candidate

Participants

components

x 3 OTC G83D [mitochondrial matrix] (Homo sapiens)

Participates

as a candidate of

other OTC variants [mitochondrial matrix] (Homo sapiens)

Disease

Name	Identifier	Synonyms
ornithine carbamoyltransferase deficiency	DOID:9271	ornithine transcarbamylase deficiency, deficiency of citrulline phosphorylase

Cross References

Mondo

0010703

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