SLC35A1,4 import CDP-ribitol

Stable Identifier
R-HSA-9940804
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane
ReviewStatus
5/5
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SLC35A1,4 import CDP-ribitol
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Both CMP-sialic acid transporter SLC35A1 and UDP-sugar transporter protein SLC35A4 transport CDP-ribitol from cytosol into the Golgi, in exchange for one molecule of CDP (Ury et al., 2021).
Literature References
PubMed ID Title Journal Year
34015330 The promiscuous binding pocket of SLC35A1 ensures redundant transport of CDP-ribitol to the Golgi

Ury, B, Potelle, S, Caligiore, F, Whorton, MR, Bommer, GT

J Biol Chem 2021
Participants
Input
Output
Participates
as an event of
Catalyst Activity

pyrimidine nucleotide transmembrane transporter activity of SLC35A1,4 [Golgi membrane]

Physical Entity
SLC35A1,4 [Golgi membrane] (Homo sapiens)
Activity
pyrimidine nucleotide transmembrane transporter activity (GO:0015218)
Orthologous Events
SLC35A1,4 import CDP-ribitol (Bos taurus)
SLC35A1,4 import CDP-ribitol (Caenorhabditis elegans)
SLC35A1,4 import CDP-ribitol (Canis familiaris)
SLC35A1,4 import CDP-ribitol (Danio rerio)
SLC35A1,4 import CDP-ribitol (Gallus gallus)
SLC35A1,4 import CDP-ribitol (Mus musculus)
SLC35A1,4 import CDP-ribitol (Plasmodium falciparum)
SLC35A1,4 import CDP-ribitol (Rattus norvegicus)
SLC35A1,4 import CDP-ribitol (Schizosaccharomyces pombe)
SLC35A1,4 import CDP-ribitol (Sus scrofa)
SLC35A1,4 import CDP-ribitol (Xenopus tropicalis)
Cross References
RHEA
Authored
Stephan, R  (2025-02-27)
Reviewed
Zaru, R  (2025-05-01)
Created
Stephan, R  (2025-03-06)
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