NS5 binds DAXX

Stable Identifier
R-HSA-9921289
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Dengue virus type 2
Compartment
nucleoplasm
ReviewStatus
5/5
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NS5 binds DAXX
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In human HEK293 cells, DENV-2 (strain 16681) nonstructural protein 5 (NS5) binds to the death-domain-associated protein (DAXX) in the nucleus. This interaction was shown to modulate RANTES chemokine production (Khunchai et al., 2012).
Literature References
PubMed ID Title Journal Year
22664104 Interaction of dengue virus nonstructural protein 5 with Daxx modulates RANTES production

Khunchai, S, Junking, M, Suttitheptumrong, A, Yasamut, U, Sawasdee, N, Netsawang, J, Morchang, A, Chaowalit, P, Noisakran, S, Yenchitsomanus, PT, Limjindaporn, T

Biochem Biophys Res Commun 2012
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
dengue disease DOID:12205 breakbone fever, Dengue Fever, classic dengue
Cross References
Mondo
Authored
Stephan, R  (2024-09-08)
Reviewed
Roque Ascenção, F  (2025-10-29)
Mansur, DS  (2025-10-29)
Created
Stephan, R  (2024-09-09)
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