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Mitochondrial genome [mitochondrial matrix]
Stable Identifier
R-HSA-9913646
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Locations in the PathwayBrowser
Expand all
DNA Replication (Homo sapiens)
Strand-asynchronous mitochondrial DNA replication (Homo sapiens)
EXOG cleaves RNA dinucleotide from nascent mitochondrial DNA (Homo sapiens)
RNA dinucleotide:nascent L strand:mitochondrial genome:RNA dinucleotide:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
nascent L strand:mitochondrial genome:nascent H strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
LIG3 (Ligase III) ligates nascent mitochondrial DNA strands (Homo sapiens)
Mitochodrial genome concatamer [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
nascent L strand:mitochondrial genome:nascent H strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
MGME1 cleaves 5' DNA flap from nascent mitochondrial DNA (Homo sapiens)
RNA dinucleotide:nascent L strand:mitochondrial genome:RNA dinucleotide:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
nascent L strand:mitochondrial genome:nascent H strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLG in the replisome polymerizes the H strand (Homo sapiens)
Mitochondrial H strand replisome with unwound replication fork [mitochondrial matrix] (Homo sapiens)
H strand RNA primer:Mitochondrial genome with unwound replication fork [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLG in the replisome polymerizes the L strand (Homo sapiens)
L strand RNA primer:nascent L strand DNA:Mitochondrial L strand replisome:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
L strand primer:Mitochondrial L strand replisome:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLG:POLG2 and TWNK (PEO1) bind mitochondrial DNA:RNA primer to form H strand replisome (Homo sapiens)
H strand RNA primer:Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial H strand replisome [mitochondrial matrix] (Homo sapiens)
H strand RNA primer:Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLRMT and POLG bind the mitochondrial L strand replication origin (OriL) (Homo sapiens)
POLRMT:POLG:PEO1:OriL:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
SSBP1:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLRMT polymerizes R-loop RNA (Homo sapiens)
POLRMT:mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
R-loop RNA:mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLRMT polymerizes RNA primer for mitochondrial L strand replication (Homo sapiens)
L strand primer:Mitochondrial L strand replisome:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
POLRMT:POLG:PEO1:OriL:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
RNASEH1 cleaves R-loop RNA to yield RNA primer for H strand polymerization (Homo sapiens)
H strand RNA primer:Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
R-loop RNA:mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
RNASEH1 cleaves RNA primer from nascent H strand, leaving RNA dinucleotides (Homo sapiens)
L strand RNA primer:nascent L strand DNA:Mitochondrial L strand replisome:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
RNA dinucleotide:nascent H strand:mitochondrial genome:L strand RNA primer:nascent L strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
RNASEH1 cleaves RNA primer from nascent L strand, leaving RNA dinucleotides (Homo sapiens)
RNA dinucleotide:nascent H strand:mitochondrial genome:L strand RNA primer:nascent L strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
RNA dinucleotide:nascent L strand:mitochondrial genome:RNA dinucleotide:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
SSBP1 binds the displaced parental H strand (Homo sapiens)
Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
SSBP1:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
TOP3A (Topoisomerase 3a) decatenates mitochondrial DNA (Homo sapiens)
Mitochodrial genome concatamer [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork (Homo sapiens)
Mitochondrial H strand replisome [mitochondrial matrix] (Homo sapiens)
H strand RNA primer:Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
Mitochondrial H strand replisome with unwound replication fork [mitochondrial matrix] (Homo sapiens)
H strand RNA primer:Mitochondrial genome with unwound replication fork [mitochondrial matrix] (Homo sapiens)
Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
NCBI Nucleotide:NC_012920 Unknown
Participates
as an output of
TOP3A (Topoisomerase 3a) decatenates mitochondrial DNA (Homo sapiens)
as a component of
POLRMT:mitochondrial genome [mitochondrial matrix] (Homo sapiens)
R-loop RNA:mitochondrial genome [mitochondrial matrix] (Homo sapiens)
H strand RNA primer:Mitochondrial genome [mitochondrial matrix] (Homo sapiens)
H strand RNA primer:Mitochondrial genome with unwound replication fork [mitochondrial matrix] (Homo sapiens)
Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
SSBP1:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand [mitochondrial matrix] (Homo sapiens)
POLRMT:POLG:PEO1:OriL:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
L strand primer:Mitochondrial L strand replisome:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
RNA dinucleotide:nascent H strand:mitochondrial genome:L strand RNA primer:nascent L strand [mitochondrial matrix] (Homo sapiens)
L strand RNA primer:nascent L strand DNA:Mitochondrial L strand replisome:Mitochondrial H strand replisome:H strand RNA primer:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
RNA dinucleotide:nascent L strand:mitochondrial genome:RNA dinucleotide:nascent H strand DNA [mitochondrial matrix] (Homo sapiens)
Mitochodrial genome concatamer [mitochondrial matrix] (Homo sapiens)
nascent L strand:mitochondrial genome:nascent H strand [mitochondrial matrix] (Homo sapiens)
Inferred To
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Bos taurus)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Caenorhabditis elegans)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Canis familiaris)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Danio rerio)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Dictyostelium discoideum)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Drosophila melanogaster)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Gallus gallus)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Mus musculus)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Plasmodium falciparum)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Rattus norvegicus)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Saccharomyces cerevisiae)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Schizosaccharomyces pombe)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Sus scrofa)
Ghost homologue of Mitochondrial genome [mitochondrial matrix]
(Xenopus tropicalis)
Cross References
ChEBI
16991
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