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SGCE [plasma membrane]
Stable Identifier
R-HSA-9913188
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Epsilon-sarcoglycan, SGCE_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Non-integrin membrane-ECM interactions (Homo sapiens)
Formation of the dystrophin-glycoprotein complex (DGC) (Homo sapiens)
DGC complex binds AGRN and HSPG2 (Homo sapiens)
DGC complex:laminins:F-actin [plasma membrane] (Homo sapiens)
DGC complex:laminins [plasma membrane] (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
DGC complex:laminins:F-actin:AGRN,HSPG2 [plasma membrane] (Homo sapiens)
DGC complex:laminins:F-actin [plasma membrane] (Homo sapiens)
DGC complex:laminins [plasma membrane] (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
DGC complex binds laminins (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
DGC complex:laminins [plasma membrane] (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
DGC:laminin complex binds F-actin (Homo sapiens)
DGC complex:laminins [plasma membrane] (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
DGC complex:laminins:F-actin [plasma membrane] (Homo sapiens)
DGC complex:laminins [plasma membrane] (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC (Homo sapiens)
DGC [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
SGC:DAG1:SSPN complex translocates to plasma membrane (Homo sapiens)
SGC:DAG1:SSPN complex [plasma membrane] (Homo sapiens)
SGCB:SGCD:SGCD,SGCZ:SGCA,SGCE [plasma membrane] (Homo sapiens)
SGCA, SGCE [plasma membrane] (Homo sapiens)
SGCE [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43556 SGCE
Gene Names
SGCE, ESG, UNQ433/PRO840
Chain
chain:1-437
Reference Genes
BioGPS Gene:8910 SGCE
COSMIC - genes:SGCE SGCE
CTD Gene:8910 SGCE
dbSNP Gene:8910 SGCE
ENSEMBL:ENSG00000127990 SGCE
HGNC:10808 SGCE
KEGG:hsa:8910 SGCE
Monarch:8910 SGCE
NCBI Gene:8910 SGCE
OMIM:604149 SGCE
UCSC:O43556 SGCE
Reference Transcript
RefSeq:NM_003919.3 SGCE
RefSeq:NM_001099401.2 SGCE
RefSeq:NM_001301139.1 SGCE
RefSeq:NM_001099400.2 SGCE
Other Identifiers
11723071_s_at
11727047_x_at
11746492_s_at
11761332_at
17059872
204688_PM_at
204688_at
3061781
3061782
3061801
3061803
3061804
3061806
3061807
3061808
3061809
3061810
3061811
3061812
3061813
3061816
3061817
3061818
3061819
3061820
3061821
3061822
3061823
3061824
3061825
3061826
3061827
3061828
3061829
3061830
3061831
3061832
3061833
3061834
3061835
3061842
3061845
3061852
3061853
3061854
3061855
3061856
3061857
41449_at
8141035
8910
A_23_P254626
A_33_P3229617
GE55132
GO:0000139
GO:0005509
GO:0005737
GO:0005789
GO:0005794
GO:0005856
GO:0005886
GO:0007155
GO:0007160
GO:0007517
GO:0016010
GO:0016012
GO:0016020
GO:0030425
GO:0032590
GO:0042383
GO:0042995
GO:0048856
HMNXSV003019300
HMNXSV003045161
ILMN_1674620
PH_hs_0019509
TC07001614.hg
g10835046_3p_s_at
Participates
as a member of
SGCA, SGCE [plasma membrane] (Homo sapiens)
Other forms of this molecule
SGCE [endoplasmic reticulum membrane]
SGCE [Golgi membrane]
Inferred To
SGCE [plasma membrane]
(Bos taurus)
SGCE [plasma membrane]
(Canis familiaris)
SGCE [plasma membrane]
(Gallus gallus)
SGCE [plasma membrane]
(Sus scrofa)
sgce [plasma membrane]
(Xenopus tropicalis)
Scgalpha [plasma membrane]
(Drosophila melanogaster)
Sgce [plasma membrane]
(Mus musculus)
Sgce [plasma membrane]
(Rattus norvegicus)
sgca-1 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001288068.1
,
NP_001092870.1
,
NP_003910.1
,
NP_001092871.1
ENSEMBL
ENST00000445866
,
ENSP00000497130
,
ENST00000648936
,
ENST00000642933
,
ENSG00000127990
,
ENSP00000398930
,
ENSP00000496237
OpenTargets
ENSG00000127990
GeneCards
SGCE
HPA
ENSG00000127990-SGCE
PRO
O43556
Pharos - Targets
O43556
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