LepB cleaves pre-EltB

Stable Identifier
R-HSA-9912371
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Escherichia coli
Compartment
periplasmic space, plasma membrane
ReviewStatus
3/5
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LepB cleaves pre-EltB
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Due to its signal sequence it is highly likely that EltB is cleaved by the LepB endopeptidase (signal peptidase I) (Zalucki et al., 2017).
Literature References
PubMed ID Title Journal Year
28088521 Signal peptidase I processed secretory signal sequences: Selection for and against specific amino acids at the second position of mature protein

Zalucki, YM, Jennings, MP

Biochem Biophys Res Commun 2017
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Output
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Catalyst Activity

serine-type endopeptidase activity of LepB [plasma membrane]

Physical Entity
LepB [plasma membrane] (Escherichia coli)
Activity
serine-type endopeptidase activity (GO:0004252)
Disease
Cross References
Mondo
Authored
Stephan, R  (2024-06-23)
Created
Stephan, R  (2024-06-08)
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