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COA3 [mitochondrial inner membrane]
Stable Identifier
R-HSA-9865341
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex IV assembly (Homo sapiens)
MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
metallochaperone complex [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
MT-CO1 mRNA is translated (Homo sapiens)
MT-CO1:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
Metallochaperone inserts 2Cu2+ into MT-CO2 (Homo sapiens)
metallochaperone complex [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
Metallochaperone inserts Cu2+ into MT-CO1 (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
metallochaperone complex [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:Mg2+:PE:CL:MITRAC [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC (Homo sapiens)
MT-CO1:Mg2+:PE:CL:MITRAC [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MITRAC [mitochondrial inner membrane] (Homo sapiens)
COA3 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y2R0 COA3
Gene Names
COA3, CCDC56, MITRAC12, HSPC009
Chain
initiator methionine:, chain:2-106
Reference Genes
BioGPS Gene:28958 COA3
COSMIC (genes):COA3 COA3
CTD Gene:28958 COA3
dbSNP Gene:28958 COA3
ENSEMBL:ENSG00000183978 COA3
HGNC:24990 COA3
KEGG:hsa:28958 COA3
Monarch:28958 COA3
NCBI Gene:28958 COA3
OMIM:614775 COA3
UCSC:Q9Y2R0 COA3
Reference Transcript
RefSeq:NM_001040431.2 COA3
Other Identifiers
11744040_a_at
11761716_at
16845259
218026_PM_at
218026_at
236998_PM_at
236998_at
28958
3758145
3758149
3758150
3758151
3758153
44713_at
78634_at
8015712
ADDON002594.hg
A_23_P100802
A_24_P356453
GE58545
GO:0005515
GO:0005739
GO:0005743
GO:0033617
GO:0043226
GO:0065003
GO:0070131
HMNXSV003006799
Hs.134555.0.A1_3p_at
ILMN_2064898
PH_hs_0039469
TC17001544.hg
g7661731_3p_at
Participates
as a component of
MITRAC [mitochondrial inner membrane] (Homo sapiens)
metallochaperone complex [mitochondrial inner membrane] (Homo sapiens)
Inferred To
Ghost homologue of COA3 [mitochondrial inner membrane]
(Gallus gallus)
COA3 [mitochondrial inner membrane]
(Bos taurus)
COA3 [mitochondrial inner membrane]
(Sus scrofa)
Coa3 [mitochondrial inner membrane]
(Mus musculus)
Coa3 [mitochondrial inner membrane]
(Rattus norvegicus)
Ccdc56 [mitochondrial inner membrane]
(Drosophila melanogaster)
coa-3 [mitochondrial inner membrane]
(Caenorhabditis elegans)
coa3a [mitochondrial inner membrane]
(Danio rerio)
CCDC56 [mitochondrial inner membrane]
(Canis familiaris)
Cross References
ENSEMBL
ENSP00000354762
,
ENST00000328434
,
ENSG00000183978
OpenTargets
ENSG00000183978
GeneCards
COA3
HPA
ENSG00000183978-COA3
PRO
Q9Y2R0
Pharos - Targets
Q9Y2R0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00395 MT-CO1
1
nascent MT-CO1 [mitochondrial inner membrane]
(R-HSA-164314)
0.612
11
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