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KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
Stable Identifier
R-HSA-9857960
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
prekallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1, prekallikrein:kininogen:cell surface receptor
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
FXIIa activates plasma kallikrein-kinin system (Homo sapiens)
Regulation of FXIIa and plasma kallikrein activity (Homo sapiens)
FXIIa is cleaved to β-FXIIa (Homo sapiens)
KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
prekallikrein:kininogen binds cell surface receptors (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
prekallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1-> kallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1 (FXIIa catalyst) (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
prekallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1-> kallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1 (PRCP catalyst) (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
prekallikrein:kininogen:cell surface receptor:factor XII -> factor XIIa + prekallikrein:kininogen:cell surface receptor (FXII autocatalysis on the cell surface) (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
prekallikrein:kininogen:cell surface receptor:factor XII -> kallikrein:kininogen:cell surface receptor:factor XII (FXII catalyst) (Homo sapiens)
KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] (Homo sapiens)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane] (Homo sapiens)
Participants
components
C1QBP, C1QBP:KRT1, PLAUR:KRT1 [plasma membrane]
(Homo sapiens)
KLKB1(20-638):KNG1(19-644) [extracellular region]
(Homo sapiens)
Participates
as an input of
prekallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1-> kallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1 (PRCP catalyst) (Homo sapiens)
prekallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1-> kallikrein:kininogen:C1QBP, C1QBP:KRT1, PLAUR:KRT1 (FXIIa catalyst) (Homo sapiens)
factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII (Homo sapiens)
as an output of
prekallikrein:kininogen:cell surface receptor:factor XII -> factor XIIa + prekallikrein:kininogen:cell surface receptor (FXII autocatalysis on the cell surface) (Homo sapiens)
prekallikrein:kininogen binds cell surface receptors (Homo sapiens)
as a component of
KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] (Homo sapiens)
Inferred To
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Bos taurus)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Canis familiaris)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Danio rerio)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Gallus gallus)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Mus musculus)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Rattus norvegicus)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Sus scrofa)
KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
(Xenopus tropicalis)
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