RSV G binds CD209,CLEC4M

Stable Identifier
R-HSA-9837376
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
plasma membrane, extracellular region, viral capsid, virion membrane
ReviewStatus
5/5
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RSV G binds CD209,CLEC4M
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Respiratory syncytial virus (RSV) glycoprotein G, as part of the RSV virion, binds to the C-type lectins CD209 (DC-SIGN) and CLEC4M (L-SIGN) on the plasma membrane inducing ERK1/2 phosphorylation (Johnson et al, 2012).
Literature References
PubMed ID Title Journal Year
22090124 Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2

Graham, BS, McLellan, JS, Johnson, TR

J Virol 2012
Participants
Input
Output
Participates
as an event of
Authored
Stephan, R  (2023-06-13)
Reviewed
Bergeron, HC  (2023-11-03)
Created
Stephan, R  (2023-06-14)
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