Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TFAP2A binds TFAP2C
Stable Identifier
R-HSA-9836270
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Specification of the neural plate border (Homo sapiens)
TFAP2A binds TFAP2C (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
TFAP2A may bind TFAP2C through an interaction between a dimerization motif in the C-terminal region of each monomer (Bosher et al. 1996, and inferred from TFAP2A homodimers in Williams and Tjian 1991a, 1991b).
Literature References
PubMed ID
Title
Journal
Year
8895516
A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma
Williams, T
,
Totty, NF
,
Bosher, JM
,
Hsuan, JJ
,
Hurst, HC
Oncogene
1996
Participants
Input
TFAP2A [nucleoplasm]
(Homo sapiens)
TFAP2C [nucleoplasm]
(Homo sapiens)
Output
TFAP2A:TFAP2C [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Specification of the neural plate border (Homo sapiens)
Orthologous Events
TFAP2A binds TFAP2C (Bos taurus)
TFAP2A binds TFAP2C (Caenorhabditis elegans)
TFAP2A binds TFAP2C (Canis familiaris)
TFAP2A binds TFAP2C (Drosophila melanogaster)
TFAP2A binds TFAP2C (Gallus gallus)
TFAP2A binds TFAP2C (Mus musculus)
TFAP2A binds TFAP2C (Rattus norvegicus)
TFAP2A binds TFAP2C (Sus scrofa)
TFAP2A binds TFAP2C (Xenopus tropicalis)
Authored
May, B (2023-05-24)
Reviewed
Patthey, C (2023-10-28)
Gunhaga, L (2023-10-28)
Created
May, B (2023-05-24)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text