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C4B-derived C4a [extracellular region]
Stable Identifier
R-HSA-981719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
C4B(680-756), C4B, CO4B_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Conversion of C4 into C4a and C4b (Homo sapiens)
C4a [extracellular region] (Homo sapiens)
C4B-derived C4a [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P0C0L5 C4B
Gene Names
C4B, CO4, CPAMD3, C4B_2
Chain
signal peptide:1-19, chain:20-675, propeptide:676-679, chain:680-1446, chain:680-756, chain:757-1446, chain:957-1336, propeptide:1447-1453, chain:1454-1744
Reference Genes
BioGPS Gene:100293534 C4B
BioGPS Gene:721 C4B
COSMIC (genes):C4B C4B
CTD Gene:100293534 C4B
CTD Gene:721 C4B
dbSNP Gene:100293534 C4B
dbSNP Gene:721 C4B
ENSEMBL:ENSG00000224389 C4B
ENSEMBL:ENSG00000224389.9 C4B
ENSEMBL:ENSG00000228267.8 C4B
ENSEMBL:ENSG00000228454.7 C4B
ENSEMBL:ENSG00000233312.8 C4B
ENSEMBL:ENSG00000236625.8 C4B
HGNC:1324 C4B
HGNC:42398 C4B
KEGG Gene (Homo sapiens):100293534 C4B
KEGG Gene (Homo sapiens):721 C4B
Monarch:100293534 C4B
Monarch:721 C4B
NCBI Gene:100293534 C4B
NCBI Gene:721 C4B
OMIM:120820 C4B
UCSC:P0C0L5 C4B
Reference Transcript
RefSeq:NM_001242823.2 C4B
RefSeq:NM_001002029.3 C4B
Other Identifiers
100293534
11734747_a_at
11749926_a_at
11754270_a_at
17007048
17007118
17028176
17030967
17031045
17035749
17038462
17041030
17041111
208451_PM_s_at
208451_s_at
214428_PM_x_at
214428_x_at
2902959
2902960
2902961
2902962
2902963
2902964
2902965
2902966
2902967
2902969
2902970
2902972
2902973
2902974
2902975
2902976
2902977
2902978
2902979
2902980
2902981
2902982
2902983
2902984
2902985
2902986
2902988
2902989
2902991
2902993
2902994
2902995
2902997
2902998
2902999
2903000
2903001
2903002
2903003
2903004
2903005
2903006
2903007
2903009
2903010
2903012
2903015
2903017
2903018
2903020
2903022
2903024
2903026
2903027
2903028
40766_at
721
74611_s_at
8118409
8118455
8179399
A_14_P137370
A_23_P42282
GE62331
GO:0001848
GO:0002376
GO:0004866
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006954
GO:0006956
GO:0006958
GO:0008228
GO:0016192
GO:0030246
GO:0030424
GO:0030425
GO:0032490
GO:0042995
GO:0043226
GO:0045087
GO:0045202
GO:0070062
GO:0072562
GO:0098542
GO:0098772
GO:0106139
GO:2000427
HMNXSV003024675
ILMN_1813695
M59815_at
PH_hs_0031857
TC06002720.hg
TC06004079.hg
TC06004080.hg
TC6_cox_hap2000227.hg
TC6_dbb_hap3000078.hg
TC6_dbb_hap3000224.hg
TC6_mcf_hap5000068.hg
TC6_mcf_hap5000197.hg
TC6_qbl_hap6000208.hg
TC6_ssto_hap7000071.hg
TC6_ssto_hap7000201.hg
g5579450_3p_s_at
Participates
as a member of
C4a [extracellular region] (Homo sapiens)
Other forms of this molecule
dNQ-C4B(757-1446) [extracellular region]
C4B alpha3 [extracellular region]
C4B alpha4 fragment [extracellular region]
C4B(956-1336) [plasma membrane]
C4B alpha [extracellular region]
S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region]
C4B(1454-1744) [extracellular region]
dNQ, ester crosslinked-C4B(757-1446) [extracellular region]
C4B(20-675) [extracellular region]
Inferred To
c4a [extracellular region]
(Xenopus tropicalis)
Tep4 [extracellular region]
(Drosophila melanogaster)
C4A [extracellular region]
(Bos taurus)
C4b [extracellular region]
(Mus musculus)
C4b [extracellular region]
(Rattus norvegicus)
Mcr [extracellular region]
(Drosophila melanogaster)
C4 [extracellular region]
(Rattus norvegicus)
Homologues of C4A-derived C4a [extracellular region]
(Caenorhabditis elegans)
Homologues of C4A-derived C4a [extracellular region]
(Drosophila melanogaster)
Homologues of C4A-derived C4a [extracellular region]
(Rattus norvegicus)
c4 [extracellular region]
(Danio rerio)
C4A-derived C4a [extracellular region]
(Caenorhabditis elegans)
C4A-derived C4a [extracellular region]
(Canis familiaris)
C4A-derived C4a [extracellular region]
(Gallus gallus)
C4A-derived C4a [extracellular region]
(Sus scrofa)
Tep2 [extracellular region]
(Drosophila melanogaster)
Tep1 [extracellular region]
(Drosophila melanogaster)
Tep3 [extracellular region]
(Drosophila melanogaster)
tep-1 [extracellular region]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001002029.3
,
NP_001229752.1
OpenTargets
ENSG00000224389
HPA
ENSG00000224389-C4B
GeneCards
P0C0L5
Ensembl
ENST00000449788
,
ENSP00000407942
,
ENSP00000364321
,
ENSP00000414200
,
ENSG00000224389
,
ENSP00000412786
,
ENSP00000415941
,
ENSG00000233312
,
ENSG00000228267
,
ENSG00000228454
,
ENST00000435500
,
ENSG00000236625
,
ENST00000435363
,
ENST00000375177
,
ENST00000411583
PRO
P0C0L5
Pharos - Targets
P0C0L5
Orphanet
17448
PDB
4XAM
,
6YSQ
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