Complement factor I binds to MCP, CR1:C4b, C3b

Stable Identifier
R-HSA-977602
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Membrane cofactor protein (MCP, CD46) and Complement Receptor 1 (CR1) act as cofactors for the protease activity of complement factor I (CFI) which binds MCP or CR1 complexes with C3b or C4b, inactivating C3b/C4b.
Literature References
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Orthologous Events
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