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KCNQ1 [plasma membrane]
Stable Identifier
R-HSA-977517
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Potassium voltage-gated channel subfamily KQT member 1, KCNQ1_HUMAN
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 2 - plateau phase (Homo sapiens)
AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Homo sapiens)
AKAP9:KCNQ1 tetramer:KCNE dimer [plasma membrane] (Homo sapiens)
KCNQ1 [plasma membrane] (Homo sapiens)
Phase 3 - rapid repolarisation (Homo sapiens)
AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Homo sapiens)
AKAP9:KCNQ1 tetramer:KCNE dimer [plasma membrane] (Homo sapiens)
KCNQ1 [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Voltage gated Potassium channels (Homo sapiens)
Activation of voltage gated Potassium channels (Homo sapiens)
Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
Kv7 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
KCNQ1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51787 KCNQ1
Gene Names
KCNQ1, KCNA8, KCNA9, KVLQT1
Chain
chain:1-676
Reference Genes
BioGPS Gene:3784 KCNQ1
COSMIC (genes):KCNQ1 KCNQ1
CTD Gene:3784 KCNQ1
dbSNP Gene:3784 KCNQ1
ENSEMBL:ENSG00000053918 KCNQ1
ENSEMBL_homo_sapiens_GENE:ENSG00000053918.19 KCNQ1
HGNC:6294 KCNQ1
KEGG Gene (Homo sapiens):3784 KCNQ1
Monarch:3784 KCNQ1
NCBI Gene:3784 KCNQ1
OMIM:607542 KCNQ1
UCSC:P51787 KCNQ1
Reference Transcript
RefSeq:NM_181798.1 KCNQ1
RefSeq:NM_000218.2 KCNQ1
Other Identifiers
11723325_a_at
11741418_a_at
11741419_x_at
16720932
204487_PM_s_at
204487_s_at
211217_PM_s_at
211217_s_at
32077_s_at
3317356
3317357
3317358
3317359
3317362
3317363
3317374
3317388
3317389
3317390
3317391
3317395
3317396
3317397
3317398
3317411
3317439
3317441
3317442
3317445
3317470
3317471
3317472
3317473
3317474
3784
40527_at
7937823
AF003743_at
A_23_P429977
GE54023
GO:0001696
GO:0001698
GO:0002027
GO:0002376
GO:0003012
GO:0003013
GO:0003014
GO:0005215
GO:0005216
GO:0005249
GO:0005251
GO:0005267
GO:0005515
GO:0005516
GO:0005546
GO:0005737
GO:0005764
GO:0005768
GO:0005769
GO:0005770
GO:0005773
GO:0005783
GO:0005886
GO:0005929
GO:0005975
GO:0006006
GO:0006811
GO:0006813
GO:0006814
GO:0007507
GO:0007605
GO:0007622
GO:0008016
GO:0008076
GO:0008157
GO:0008217
GO:0008289
GO:0010460
GO:0015271
GO:0015705
GO:0016020
GO:0016323
GO:0016324
GO:0022600
GO:0023052
GO:0030133
GO:0030154
GO:0030218
GO:0030644
GO:0030659
GO:0031410
GO:0032868
GO:0034220
GO:0034236
GO:0034237
GO:0034702
GO:0034705
GO:0035176
GO:0035934
GO:0042472
GO:0043005
GO:0043025
GO:0043226
GO:0044325
GO:0044782
GO:0045121
GO:0045177
GO:0048839
GO:0048856
GO:0050877
GO:0050886
GO:0050892
GO:0050910
GO:0055064
GO:0055065
GO:0055075
GO:0055085
GO:0060048
GO:0060117
GO:0060306
GO:0060307
GO:0060372
GO:0060452
GO:0060453
GO:0061337
GO:0062094
GO:0070293
GO:0070294
GO:0071320
GO:0071466
GO:0071805
GO:0071872
GO:0071875
GO:0086005
GO:0086008
GO:0086009
GO:0086011
GO:0086013
GO:0086014
GO:0086089
GO:0086091
GO:0090102
GO:0097110
GO:0097546
GO:0097623
GO:0098576
GO:0098914
GO:0098915
GO:1901381
GO:1902260
GO:1902282
GO:1903817
GO:1905515
GO:1990573
GO:1990794
HMNXSV003058301
ILMN_1656079
ILMN_1806150
ILMN_2409520
PH_hs_0024049
TC11000066.hg
TC11002520.hg
U40990_at
g2961248_3p_a_at
g4557688_3p_a_at
p33660
Participates
as a member of
Kv7 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
as a component of
AKAP9:KCNQ1 tetramer:KCNE dimer [plasma membrane] (Homo sapiens)
Inferred To
KCNQ1 [plasma membrane]
(Bos taurus)
KCNQ1 [plasma membrane]
(Gallus gallus)
Kcnq1 [plasma membrane]
(Mus musculus)
Kcnq1 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_000209.2
,
NP_861463.1
Guide to Pharmacology - Targets
560
OpenTargets
ENSG00000053918
ZINC - Substances
KCNQ1_HUMAN
ZINC target
P51787
PRO
P51787
PDB
7XNI
,
7XNK
,
8SIM
,
6UZZ
,
8SIN
,
3HFE
,
7VUO
,
7VVH
,
3HFC
,
7XNL
,
4UMO
,
3BJ4
,
7XNN
,
6MIE
,
8SIK
,
6V01
,
6V00
,
4V0C
,
7VVD
GeneCards
P51787
HPA
ENSG00000053918-KCNQ1
Ensembl
ENSP00000155840
,
ENST00000155840
,
ENSG00000053918
,
ENST00000335475
,
ENSP00000334497
Pharos - Targets
P51787
Orphanet
16295
ZINC - Predictions - Purchasable
KCNQ1_HUMAN
HMDB Protein
HMDBP02530
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