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HCN2 [plasma membrane]
Stable Identifier
R-HSA-977502
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, HCN2_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
HCN channels (Homo sapiens)
Activation of HCN channels (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunt HCN2 [plasma membrane] (Homo sapiens)
HCN2 [plasma membrane] (Homo sapiens)
Binding of cAMP to HCN channels (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunt HCN2 [plasma membrane] (Homo sapiens)
HCN2 [plasma membrane] (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunt HCN2 [plasma membrane] (Homo sapiens)
HCN2 [plasma membrane] (Homo sapiens)
HCNs:cAMP bind SNIs (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunt HCN2 [plasma membrane] (Homo sapiens)
HCN2 [plasma membrane] (Homo sapiens)
HCNs:cAMP:SNIs [plasma membrane] (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunt HCN2 [plasma membrane] (Homo sapiens)
HCN2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UL51 HCN2
Gene Names
HCN2, BCNG2
Chain
chain:1-889
Reference Genes
BioGPS Gene:610 HCN2
COSMIC (genes):HCN2 HCN2
CTD Gene:610 HCN2
dbSNP Gene:610 HCN2
ENSEMBL:ENSG00000099822 HCN2
ENSEMBL:ENSG00000099822.3 HCN2
HGNC:4846 HCN2
KEGG Gene (Homo sapiens):610 HCN2
Monarch:610 HCN2
NCBI Gene:610 HCN2
OMIM:602781 HCN2
UCSC:Q9UL51 HCN2
Reference Transcript
RefSeq:NM_001194.3 HCN2
Other Identifiers
11732497_at
11732498_at
16856216
207592_PM_s_at
207592_s_at
214893_PM_x_at
214893_x_at
34520_at
3586297
3586301
3586303
3616457
3616467
3616469
3616471
3815046
3815047
3815048
3815052
3815054
3815055
3815056
3815057
3815058
3815059
3815060
3815061
3815062
3815063
3815064
3815065
3815066
3815067
610
8023984
A_23_P342612
A_33_P3279640
A_33_P3345586
GE55208
GO:0000166
GO:0003013
GO:0003254
GO:0005215
GO:0005216
GO:0005222
GO:0005244
GO:0005248
GO:0005249
GO:0005267
GO:0005272
GO:0005515
GO:0005886
GO:0006811
GO:0006813
GO:0006814
GO:0007267
GO:0008076
GO:0016020
GO:0023052
GO:0030424
GO:0030425
GO:0030552
GO:0034765
GO:0035725
GO:0042391
GO:0042802
GO:0055085
GO:0071320
GO:0071321
GO:0071805
GO:0086012
GO:0086091
GO:0098719
GO:0098855
GO:0098907
GO:0110165
GO:1990573
GO:2001257
HMNXSV003020815
Hs.124161.1.A1_3p_a_at
ILMN_1659150
ILMN_2182101
TC19000010.hg
TC19001926.hg
g10835003_3p_x_at
Participates
as a component of
HCN channel Homomer of subunt HCN2 [plasma membrane] (Homo sapiens)
Inferred To
Ih [plasma membrane]
(Drosophila melanogaster)
HCN2 [plasma membrane]
(Bos taurus)
HCN2 [plasma membrane]
(Canis familiaris)
HCN2 [plasma membrane]
(Danio rerio)
HCN2 [plasma membrane]
(Gallus gallus)
HCN2 [plasma membrane]
(Mus musculus)
HCN2 [plasma membrane]
(Rattus norvegicus)
HCN2 [plasma membrane]
(Sus scrofa)
HCN2 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001185.3
Guide to Pharmacology - Targets
401
OpenTargets
ENSG00000099822
ZINC - Substances
HCN2_HUMAN
ZINC target
Q9UL51
PRO
Q9UL51
PDB
3U10
,
2MPF
GeneCards
Q9UL51
HPA
ENSG00000099822-HCN2
Ensembl
ENSG00000099822
,
ENSP00000251287
,
ENST00000251287
Pharos - Targets
Q9UL51
Orphanet
24587
ZINC - Predictions - Purchasable
HCN2_HUMAN
HMDB Protein
HMDBP02618
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
3',5'-cyclic GMP [ChEBI:16356]
1
cGMP [cytosol]
(R-ALL-30991)
0.683
4
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