HOXC8 binds CDH11 gene promoter

Stable Identifier
R-HSA-9760641
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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HOXC8 binds CDH11 gene promoter
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HOXC8 (Homeobox protein Hox-C8) binds to the CDH11 gene promoter at the position -196 to -191, which is one of the three putative HOX protein-binding sequences in the CDH11 promoter (Li et al. 2014). Mouse Hoxc8 was also shown to bind to the mouse Cdh11 gene promoter (Lei et al. 2006) and upregulate mouse Cdh11 gene transcription (Lei et al. 2005, Lei et al. 2006).
Literature References
PubMed ID Title Journal Year
24810778 HOXC8 promotes breast tumorigenesis by transcriptionally facilitating cadherin-11 expression

Huang, S, Li, Y, Liu, D, Chao, F, Kim, J, Huang, B

Oncotarget 2014
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Authored
Orlic-Milacic, M  (2022-06-02)
Reviewed
Brasch, J  (2023-04-18)
Created
Orlic-Milacic, M  (2021-12-20)
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