Reactome | MeR25,27-CNBP [cytosol]

MeR25,27-CNBP [cytosol]

Stable Identifier

R-HSA-9759641

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

MeR25,27-RNF163, MeR25,27-ZNF9, CCHC-type zinc finger nucleic acid binding protein, Cellular nucleic acid-binding protein

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - SARS-CoV Infections (Homo sapiens)
    - SARS-CoV-2 Infection (Homo sapiens)
      - SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
        
        CNBP binds SARS-CoV-2 G-rich RNA (Homo sapiens)
        
        MeR25,27-CNBP [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P62633 CNBP

Gene Names

CNBP, RNF163, ZNF9

Chain

initiator methionine:1, chain:2-177

Reference Genes

BioGPS Gene:7555 CNBP

COSMIC (genes):CNBP CNBP

CTD Gene:7555 CNBP

dbSNP Gene:7555 CNBP

ENSEMBL:ENSG00000169714.17 CNBP

HGNC:13164 CNBP

KEGG Gene (Homo sapiens):7555 CNBP

Monarch:7555 CNBP

NCBI Gene:7555 CNBP

OMIM:116955 CNBP

UCSC:P62633 CNBP

Reference Transcript

Other Identifiers

0005270181

11727419_x_at

11727420_at

11744487_x_at

11744825_a_at

11754038_a_at

11754039_x_at

16958953

206158_PM_s_at

206158_s_at

227731_PM_at

227731_at

2674347

2694643

2694645

2694646

2694647

2694648

2694649

2694650

2694651

2694653

2694656

2694658

2694661

32841_at

59354_at

7555

7894036

8090546

A_24_P664939

GE81275

GO:0000122

GO:0002181

GO:0003676

GO:0003677

GO:0003697

GO:0003723

GO:0003727

GO:0003729

GO:0005515

GO:0005622

GO:0005634

GO:0005737

GO:0005783

GO:0005829

GO:0006351

GO:0006355

GO:0008270

GO:0008284

GO:0042632

GO:0043226

GO:0045182

GO:0045893

GO:0045944

GO:0046872

GO:0051880

GO:0071919

GO:2000767

HMNXSV003043943

Hs.113660.0.S1_3p_at

ILMN_1769319

ILMN_1804631

ILMN_2169839

ILMN_3250201

ILMN_3250984

PH_hs_0000280

PH_hs_0040434

TC03001766.hg

U19765_at

g4827070_3p_a_at

This entity regulates

Negatively

CNBP binds SARS-CoV-2 G-rich RNA (Homo sapiens)

Other forms of this molecule

CNBP [cytosol]

Modified Residues

Name

omega-N-methyl-L-arginine at 25

Coordinate

PsiMod Name

omega-N-methyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.

Name

omega-N-methyl-L-arginine at 27

Coordinate

PsiMod Name

omega-N-methyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.

Cross References

RefSeq

NP_003409.1, NP_001120664.1, NP_001120666.1, NP_001120665.1, NP_001120668.1, NP_001120667.1

OpenTargets

ENSG00000169714

GeneCards

P62633

HPA

ENSG00000169714-CNBP

Ensembl

ENST00000500450, ENSP00000426223, ENSP00000421323, ENSG00000169714, ENSP00000399488, ENST00000441626, ENST00000451728, ENSP00000410769, ENST00000422453, ENST00000502976, ENSP00000410619, ENST00000446936, ENST00000504813, ENSP00000400444, ENSP00000422110

PRO

P62633

Pharos - Targets

P62633

Orphanet

15756

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
IntAct:EBI-26956331 +3467 (NSP3)			0.558	2
IntAct:EBI-26956583 -13,963 (NSP12)			0.558	2
IntAct:EBI-26956485 -23,877 (NSP3)			0.558	2
IntAct:EBI-26956558 +644 (NSP1)			0.558	2
UniProt:Q63009	2	PRMT1 [nucleoplasm] (R-RNO-3215140) PRMT1 [cytosol] (R-RNO-9632173)	0.558	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4