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PREDN,PREDL diffuse into GI cells
Stable Identifier
R-HSA-9757540
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol
,
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Drug ADME (Homo sapiens)
Prednisone ADME (Homo sapiens)
PREDN,PREDL diffuse into GI cells (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As highly hydrophobic compounds prednisone and prednisolone move along their concentration gradients into cells by simple diffusion, passing through membrane bilayers (Plagemann and Erbe, 1976).
Literature References
PubMed ID
Title
Journal
Year
182169
Glucocorticoids--uptake by simple diffusion by cultured Reuber and Novikoff rat hepatoma cells
Erbe, J
,
Plagemann, PG
Biochem Pharmacol
1976
Participants
Input
PREDN,PREDL [extracellular region]
Output
PREDN,PREDL [cytosol]
Participates
as an event of
Prednisone ADME (Homo sapiens)
Authored
Stephan, R (2021-10-27)
Reviewed
Thorn, CF (2022-08-05)
Created
Stephan, R (2021-11-02)
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