BCMO1:Fe2+ cleaves betaC to atRAL

Stable Identifier
R-HSA-975635
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Oxidative cleavage of beta-carotene to all-trans-retinal
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As long as vitamin A is needed, beta-carotene-monooxygenase (BCMO1) catalyses the cleavage of carotenes, resulting mainly in retinal (Fierce et al. 2008).

Literature References
PubMed ID Title Journal Year
18295589 In vitro and in vivo characterization of retinoid synthesis from beta-carotene

Fierce, Y, de Morais Vieira, M, Piantedosi, R, Wyss, A, Blaner, WS, Paik, J

Arch Biochem Biophys 2008
Participants
Output
Participant Of
Catalyst Activity
Catalyst Activity
Title
beta-carotene 15,15'-monooxygenase activity of BCMO1:Fe2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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