Reactome | GABRR2 [plasma membrane]

GABRR2

Stable Identifier

R-HSA-975444

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Gamma-aminobutyric acid receptor subunit rho-2, GBRR2_HUMAN

Locations in the PathwayBrowser

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Neuronal System (Homo sapiens)

- Transmission across Chemical Synapses (Homo sapiens)
  - Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
    - GABA receptor activation (Homo sapiens)
      - GABA A (rho) receptor activation (Homo sapiens)
        
        GABRR pentamer:GABA transports extracellular Cl- to cytosol (Homo sapiens)
        
        GABRR pentamer:GABA [plasma membrane] (Homo sapiens)
        
        GABRR1-3 [plasma membrane] (Homo sapiens)
        
        GABRR2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P28476 GABRR2

Gene Names

GABRR2

Chain

signal peptide:1-20, chain:21-465

Reference Genes

BioGPS Gene:2570 GABRR2

COSMIC (genes):GABRR2 GABRR2

CTD Gene:2570 GABRR2

dbSNP Gene:2570 GABRR2

ENSEMBL:ENSG00000111886 GABRR2

HGNC:4091 GABRR2

KEGG Gene (Homo sapiens):hsa:2570 GABRR2

Monarch:2570 GABRR2

NCBI Gene:2570 GABRR2

OMIM:137162 GABRR2

UCSC:P28476 GABRR2

Reference Transcript

RefSeq:NM_002043.4 GABRR2

Other Identifiers

0006380358

11748595_a_at

17021573

208217_at

2570

31551_at

8128099

CCDS5020

ENSG00000111886

ENSP00000386029

ENST00000402938

EntrezGene:2570

g4503870_3p_at

GABRR2

GABRR2-201

GE561327

GO:0004890

GO:0005216

GO:0005230

GO:0005254

GO:0005886

GO:0005887

GO:0006810

GO:0006811

GO:0006821

GO:0007165

GO:0007214

GO:0007268

GO:0007601

GO:0016020

GO:0016021

GO:0019904

GO:0030054

GO:0034220

GO:0034707

GO:0045202

GO:0045211

GO:1902476

GO:1902711

HGNC:4091

ILMN_1676870

M86868_at

MIM:137162

NM_002043

NP_002034

PF02931

PF02932

PH_hs_0005585

PR00252

PR00253

PR01670

PR01672

TC06001939.hg

uc003pnb.4

UPI000012B0DB

XM_011535713

XM_011535714

XM_011535715

XM_011535716

XM_011535717

XP_011534015

XP_011534016

XP_011534017

XP_011534018

XP_011534019

Participant Of

hasMember

GABRR1-3 [plasma membrane]

Inferred To

GABRR2 [plasma membrane] (Bos taurus)

GABRR2 [plasma membrane] (Caenorhabditis elegans)

GABRR2 [plasma membrane] (Canis familiaris)

GABRR2 [plasma membrane] (Danio rerio)

GABRR2 [plasma membrane] (Drosophila melanogaster)

GABRR2 [plasma membrane] (Gallus gallus)

GABRR2 [plasma membrane] (Mus musculus)

GABRR2 [plasma membrane] (Rattus norvegicus)

GABRR2 [plasma membrane] (Sus scrofa)

GABRR2 [plasma membrane] (Taeniopygia guttata)

GABRR2 [plasma membrane] (Xenopus tropicalis)

Homologues of GABRR2 [plasma membrane] (Bos taurus)

Homologues of GABRR2 [plasma membrane] (Canis familiaris)

Homologues of GABRR2 [plasma membrane] (Danio rerio)

Homologues of GABRR2 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_002034.3

ZINC - Metabolites

GBRR2_HUMAN

ZINC - Substances

GBRR2_HUMAN

GeneCards

P28476

ZINC target

P28476

ZINC - Biogenic

GBRR2_HUMAN

PRO

P28476

ZINC - Predictions - Purchasable

GBRR2_HUMAN

HMDB Protein

HMDBP08213