Reactome | HTR3E [plasma membrane]

HTR3E [plasma membrane]

Stable Identifier

R-HSA-975278

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

5-hydroxytryptamine receptor 3E, 5HT3E_HUMAN

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Transmission across Chemical Synapses (Homo sapiens)
  - Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
    - HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Homo sapiens)
      - HTR3 pentamers:5HT [plasma membrane] (Homo sapiens)
        
        HTR3 pentamers [plasma membrane] (Homo sapiens)
        
        2xHTR3A:3xHTR3E [plasma membrane] (Homo sapiens)
        
        HTR3E [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:A5X5Y0 HTR3E

Gene Names

HTR3E

Chain

signal peptide:1-25, chain:26-456

Reference Genes

BioGPS Gene:285242 HTR3E

COSMIC (genes):HTR3E HTR3E

CTD Gene:285242 HTR3E

dbSNP Gene:285242 HTR3E

ENSEMBL:ENSG00000186038 HTR3E

HGNC:24005 HTR3E

KEGG:hsa:285242 HTR3E

Monarch:285242 HTR3E

NCBI Gene:285242 HTR3E

OMIM:610123 HTR3E

UCSC:A5X5Y0 HTR3E

Reference Transcript

Other Identifiers

11738477_a_at

11738478_x_at

11745683_a_at

11752389_a_at

16948659

2655319

2655320

2655321

2655347

2655349

2655350

2655351

2655352

2655353

2655354

2655355

2655356

2655357

2655358

2655359

2655360

2655361

2655362

2655363

2655364

2655365

2655366

285242

8084284

GO:0004888

GO:0005215

GO:0005216

GO:0005230

GO:0005231

GO:0005515

GO:0005886

GO:0006811

GO:0007210

GO:0016020

GO:0022850

GO:0034220

GO:0043005

GO:0045202

GO:0045211

GO:0055085

GO:0060078

GO:0060079

GO:0060089

GO:0098662

GO:0140227

GO:1902495

GO:1904315

GO:1904602

HMNXSV003015123

ILMN_1778277

PH_hs_0026242

TC03000991.hg

Participates

as a component of

2xHTR3A:3xHTR3E [plasma membrane] (Homo sapiens)

Inferred To

lgc-7 [plasma membrane] (Caenorhabditis elegans)

lgc-9 [plasma membrane] (Caenorhabditis elegans)

lgc-4 [plasma membrane] (Caenorhabditis elegans)

lgc-12 [plasma membrane] (Caenorhabditis elegans)

lgc-31 [plasma membrane] (Caenorhabditis elegans)

lgc-6 [plasma membrane] (Caenorhabditis elegans)

acr-20 [plasma membrane] (Caenorhabditis elegans)

lgc-11 [plasma membrane] (Caenorhabditis elegans)

lgc-8 [plasma membrane] (Caenorhabditis elegans)

HTR3E [plasma membrane] (Canis familiaris)

HTR3E [plasma membrane] (Sus scrofa)

deg-3 [plasma membrane] (Caenorhabditis elegans)

acr-23 [plasma membrane] (Caenorhabditis elegans)

LOC616094 [plasma membrane] (Bos taurus)

acr-5 [plasma membrane] (Caenorhabditis elegans)

lgc-10 [plasma membrane] (Caenorhabditis elegans)

acr-24 [plasma membrane] (Caenorhabditis elegans)

Homologues of HTR3E [plasma membrane] (Caenorhabditis elegans)

acr-21 [plasma membrane] (Caenorhabditis elegans)

lgc-5 [plasma membrane] (Caenorhabditis elegans)

des-2 [plasma membrane] (Caenorhabditis elegans)

lgc-30 [plasma membrane] (Caenorhabditis elegans)

Cross References

Guide to Pharmacology - Targets

377

ENSEMBL

ENST00000425359, ENSP00000395833, ENST00000415389, ENST00000436361, ENST00000440596, ENST00000335304, ENSP00000335511, ENSP00000401444, ENSP00000406050, ENSP00000401900, ENSG00000186038

OpenTargets

ENSG00000186038

GeneCards

HTR3E

HPA

ENSG00000186038-HTR3E

PRO

A5X5Y0

Pharos - Targets

A5X5Y0

GlyGen

A5X5Y0

HMDB Protein

HMDBP12056

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75915 ARL6IP5	1	ARL6IP5 [cytosol] (R-HSA-2980942)	0.527	3

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