SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PSMC6

Stable Identifier
R-HSA-9727908
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
cytosol
ReviewStatus
5/5
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SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PSMC6
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
SARS-CoV-1 nucleocapsid protein interacts with proteasome subunit p42 (PSMC6). Proteasomes play a central role in the degradation of short-lived and regulatory host proteins. They are also capable of degrading exogenous proteins like viral peptides (Wang et al, 2010).
Literature References
PubMed ID Title Journal Year
20478047 Interactions of SARS coronavirus nucleocapsid protein with the host cell proteasome subunit p42

Li, J, Wang, Q, Guan, W, Li, D, Yu, J, Liang, M, Wang, T, Li, C, Zhang, Q

Virol J 2010
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Authored
Stephan, R  (2021-04-16)
Reviewed
D'Eustachio, P  (2021-01-26)
Created
Stephan, R  (2021-04-19)
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