Reactome | PLEKHG4B [cytosol]

PLEKHG4B [cytosol]

Stable Identifier

R-HSA-9714841

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - CDC42 GTPase cycle (Homo sapiens)
        
        CDC42 GEFs activate CDC42 (Homo sapiens)
        
        CDC42 GEFs [cytosol] (Homo sapiens)
        
        PLEKHG4B [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96PX9 PLEKHG4B

Gene Names

PLEKHG4B, KIAA1909

Chain

chain:1-1627

Reference Genes

COSMIC (genes):PLEKHG4B PLEKHG4B

ENSEMBL:ENSG00000153404 PLEKHG4B

HGNC:29399 PLEKHG4B

OMIM:620665 PLEKHG4B

UCSC:Q96PX9 PLEKHG4B

Reference Transcript

RefSeq:XM_006714446.3 PLEKHG4B

Other Identifiers

11733471_at

11741740_at

11763349_at

153478

16982479

16982483

16982508

230441_PM_at

230441_at

230671_PM_at

230671_at

236255_PM_at

236255_at

2798458

2798464

2798468

2798470

2798472

2798474

2798477

2798478

2798479

2798482

2798484

2798485

2798486

2798487

2798488

2798489

2798490

2798492

2798493

2798494

2798495

2798496

2798499

2798501

2798502

2798503

2798504

2798505

2798507

2798512

2798513

2798515

2798517

2798519

2798520

2798521

2798523

2798525

2798527

2798528

2798529

2798531

54858_at

61749_at

74182_at

8104141

8104163

ADDON002486.hg

A_21_P0012938

A_23_P81640

A_32_P129269

A_33_P3253538

A_33_P3649715

A_33_P3746549

GE519842

GE695661

GE865669

GO:0005085

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0005911

GO:0007155

GO:0007411

GO:0009925

GO:0019898

GO:0043226

GO:0051056

GO:0070161

GO:0098609

GO:0098772

HMNXSV003001153

HMNXSV003017500

HMNXSV003034149

HMNXSV003056904

HMNXSV003057456

Hs.103142.0.A1_3p_at

Hs.109057.0.A1_3p_at

Hs.127804.0.A1_3p_at

ILMN_1702020

ILMN_1814647

ILMN_1853093

ILMN_2241252

PH_hs_0007352

PH_hs_0026319

PH_hs_0032560

PH_hs_0036078

TC05000001.hg

TC05000002.hg

TC05000003.hg

TC05002171.hg

TC05002172.hg

p13555

p13556

Participates

as a member of

CDC42 GEFs [cytosol] (Homo sapiens)

Inferred To

Dmel\CG15611 [cytosol] (Drosophila melanogaster)

CG15612 [cytosol] (Drosophila melanogaster)

trio [cytosol] (Drosophila melanogaster)

Arhgef25 [cytosol] (Mus musculus)

Arhgef25 [cytosol] (Rattus norvegicus)

ARHGEF25 [cytosol] (Bos taurus)

ARHGEF25 [cytosol] (Canis familiaris)

ARHGEF25 [cytosol] (Sus scrofa)

unc-73 [cytosol] (Caenorhabditis elegans)

Homologues of PLEKHG4B [cytosol] (Drosophila melanogaster)

arhgef25 [cytosol] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000283426, ENSP00000283426, ENSG00000153404

OpenTargets

ENSG00000153404

GeneCards

PLEKHG4B

HPA

ENSG00000153404-PLEKHG4B

PRO

Q96PX9

Pharos - Targets

Q96PX9

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.488	2

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