KW2449-sensitive FLT3 mutants [plasma membrane]

Stable Identifier
R-HSA-9699543
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
19541823 KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation

Shiotsu, Y, Kiyoi, H, Ishikawa, Y, Tanizaki, R, Shimizu, M, Umehara, H, Ishii, K, Mori, Y, Ozeki, K, Minami, Y, Abe, A, Maeda, H, Akiyama, T, Kanda, Y, Sato, Y, Akinaga, S, Naoe, T

Blood 2009
28077790 FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors

Nguyen, B, Williams, AB, Young, DJ, Ma, H, Li, L, Levis, M, Brown, P, Small, D

Oncotarget 2017
22858906 Mutations of FLT3/ITD confer resistance to multiple tyrosine kinase inhibitors

Williams, AB, Nguyen, B, Li, L, Brown, P, Levis, M, Leahy, D, Small, D

Leukemia 2013
Participants
Participant Of
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
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